Product nameAnti-Streptococcus pyogenes Group A Carbohydrate antibody
DescriptionGoat polyclonal to Streptococcus pyogenes Group A Carbohydrate
SpecificityStreptococcus Pyogenes Group A
Tested applicationsSuitable for: Dot blot, ELISA, ICC/IF, IHC-Fr, IP, WB, IHC-Pmore details
Species reactivityReacts with: Other species
Goats were intensely immunized, intravenously, with killed Streptococcus pyogenes vaccine Strain J17A4.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Constituent: 0.0268% PBS
Concentration information loading...
PurityImmunogen affinity purified
Purification notesSerum was collected and antibody to the Group A carbohydrate was immunoaffinity purified
Our Abpromise guarantee covers the use of ab9191 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
RelevanceStreptococcus pyogenes (Group A streptococcus) is a Gram-positive, nonmotile, nonsporeforming coccus that occurs in chains or in pairs of cells. Individual cells are round-to-ovoid cocci, 0.6-1.0 micrometer in diameter. Streptococci divide in one plane and thus occur in pairs or (especially in liquid media or clinical material) in chains of varying lengths. The metabolism of S. pyogenes is fermentative; the organism is a catalase-negative aerotolerant anaerobe (facultative anaerobe), and requires enriched medium containing blood in order to grow. Group A streptococci typically have a capsule composed of hyaluronic acid and exhibit beta (clear) hemolysis on blood agar.
This product has been referenced in:
- Sumitomo T et al. Streptococcal Cysteine Protease-Mediated Cleavage of Desmogleins Is Involved in the Pathogenesis of Cutaneous Infection. Front Cell Infect Microbiol 8:10 (2018). IHC-P . Read more (PubMed: 29416987) »
- Rush JS et al. The molecular mechanism of N-acetylglucosamine side-chain attachment to the Lancefield group A carbohydrate in Streptococcus pyogenes. J Biol Chem 292:19441-19457 (2017). Read more (PubMed: 29021255) »