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Anti-Streptokinase antibody (ab35168)

Submit a review Q&A (6)References (2)

Key features and details

  • Rabbit polyclonal to Streptokinase
  • Suitable for: ELISA
  • Reacts with: Species independent
  • Isotype: IgG

Overview

  • Product name

    Anti-Streptokinase antibody

  • Description

    Rabbit polyclonal to Streptokinase

  • Host species

    Rabbit

  • Tested applications

    Suitable for: ELISAmore details

  • Species reactivity

    Reacts with: Species independent

  • Immunogen

    Full length native protein.

  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

  • Storage buffer

    pH: 7.20
    Preservative: 0.1% Sodium azide
    Constituent: PBS
  • Concentration information loading...

  • Purification notes

    Ammonium sulphate fractionation.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Research areas

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab35168 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
Notes
Application notes
ELISA: 1/1000 - 1/5000. In a simple ELISA with 0.5µg Streptokinase coated per well, the 50% OD was observed at an antibody dilution of 1/2500. Under the same conditions the end point was observed at 1/50000.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

  • Relevance

    Streptokinase is a metallo-enzyme produced by various strains of Streptococcus that can liquify blood clots by converting plasminogen to plasmin. Streptokinase is not a protease but it activates plasminogen by complexing with it. It is thought to prevent the formation of effective fibrin barriers around the site of infection, thereby contributing to the invasiveness of the cells.

  • Alternative names

    • ska antibody
    • skc antibody
    • skg antibody

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (2)

Publishing research using ab35168? Please let us know so that we can cite the reference in this datasheet.

ab35168 has been referenced in 2 publications.

  • Andreoni F  et al. Immunoglobulin Attenuates Streptokinase-Mediated Virulence in Streptococcus dysgalactiae Subspecies equisimilis Necrotizing Fasciitis. J Infect Dis 217:270-279 (2018). PubMed: 29099935
  • Kinnby B  et al. Plasminogen binding by oral streptococci from dental plaque and inflammatory lesions. Microbiology 154:924-31 (2008). PubMed: 18310038

Customer reviews and Q&As

Show All Reviews Q&A
Submit a review Submit a question

1-6 of 6 Abreviews or Q&A

Question

Please provide certificate of compliance (CoC) for Ab35168.
Regards

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Answer

Thank you for contacting us.

Please find attached the requested document. I have included the lot number from your purchase order 1211891. Please let me if this is not correct.


I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

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Question

IU is International unit. IU / mL represent the activity of the regent.

In COA the protein content of the antibody is given as 5 mg/mL. so customer require the activity in IU/mL.

Regards,

Read More
Answer

Thank you for your reply.

IU is used in diagnostics and is used to quantify vitamins, hormones, some medications, vaccines, blood products, and similar biologically active substances.

Our product including this antibody are not for diagnostic purposes and for research only.

Therefore the IU of this antibody is not tested and measured. We can only provide the protein concentration which is 5 mg/ml.


I am sorry to not be able to provide an answer on this occasion and hope this information is nevertheless helpful.

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Question

Hi,

Is it possible to provide expiry date in this ?

Regards

xxxxx

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Answer

Thank you for your enquiry.

We do not have set expiration dates for our products. Most antibodies are stable and can last for anywhere from a few months to several years if stored properly, so we strongly recommend that you follow the storage instructions on the datasheet for the antibody you purchased. These conditions will vary among our antibodies, therefore, it is important to verify the storage conditions for each of our products when you receive them. We guarantee all of our products to work for at least 120 days from the date of purchase when stored correctly.

For more information on antibody storage and stability, please visit our Antibody Storage Guide on our Protocols and Troubleshooting Tips page (https://www.abcam.com/index.html?pageconfig=resource&rid=10795).

I hope this information helps. Please do not hesitate to contact us if you need anything further.

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Question

Please send the COA.

The lot number is GR21051-2.

Regards,

Read More
Answer

Thank you for contacting us.

Please find the Certificate of Compliance as requested attached to this email.

If you have any further questions please do not hesitate to contact us again.

Read More

Question

Thank you. Are you writing the Manufacturing & expiry date in COA ?

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Answer

Thank you for your reply.


This information is not typically included in a Certificate of Compliance. Some of our antibodies are produced in-house and others are sourced from suppliers or academic collaborators whose products we believe will be of interest to our customers. Some of our collaborators are not certified ISO9001 and so we are not able to provide a certificate of analysis for these particular products.


As the identity of our collaborators is confidential, we provide a certificate of compliance for all of our products available in our catalogue. This document certifies that our products meet the required specifications for a particular lot/batch of product.


I can include expiration information if this is required by the end user. I hope this information is helpful. Please do not hesitate to contact me if you have any additional questions.

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Question

Kindly arrange to send COA ( Certificate of Analysis) of the following products ( which lot is available )

code no. ab35168

Kindly treat as urgent.

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Answer

Thank you for contacting Abcam.


Attached please find the Certificate of Compliance document for this antibody.


I hope this information is helpful. Please do not hesitate to contact me if you have any additional questions.

Read More

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