Overview

  • Product name

    Streptomycin sulfate, protein synthesis inhibitor
  • Description

    Aminoglycoside antibiotic, protein synthesis inhibitor
  • Biological description

    Aminoglycoside antibiotic, protein synthesis inhibitor. Binds to the small S12 rRNA of the 30S subunit of bacterial ribosome. Inhibits microbial cell death.
  • CAS Number

    3810-74-0
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-[(1R,2R,3S,4R,5R,6S)-3-(Diaminomethylideneamino)-4-[(2R,3R,4R,5S)-3-[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine sesquisulfate
  • Molecular weight

    728.69
  • Molecular formula

    C21H39N7O12.1.5H2SO4
  • PubChem identifier

    520882
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 75 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1C(C(C(O1)OC2C(C(C(C(C2O)O)[NH+]=C(N)N)O)[NH+]=C(N)N)OC3C(C(C(C(O3)CO) O)O)[NH2+]C)(C=O)O.CC1C(C(C(O1)OC2C(C(C(C(C2O)O)[NH+]=C(N)N)O)[NH+]=C(N) N)OC3C(C(C(C(O3)CO)O)O)[NH2+]C)(C=O)O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O- ].[O-]S(=O)(=O)[O-]
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Bencsik AA  et al. New insights into early sequential PrPsc accumulation in scrapie infected mouse brain evidenced by the use of streptomycin sulfate. Histochem Cell Biol 129:643-50 (2008). Read more (PubMed: 18224331) »
  • An YX  et al. [The intervention of tetrandrine in the acute renal injury induced by streptomycin sulfate in puinea pigs]. Fen Zi Xi Bao Sheng Wu Xue Bao 40:113-20 (2007). Read more (PubMed: 17580664) »
  • Yamashita H  et al. Expression of fibroblast growth factor receptor in adult mouse utricle damaged by streptomycin sulfate. ORL J Otorhinolaryngol Relat Spec 60:1-3 (0). Read more (PubMed: 9519373) »

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