Overview

  • Product name

  • Description

    Rabbit polyclonal to Sts1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 117-291 of Human Sts1 (NP_116262).

  • Positive control

    • 293T whole cell lysate, A431 whole cell lysate, Jurkat whole cell lysate, Raji whole cell lysate
  • General notes

    Keep as concentrated solution.

Properties

Applications

Our Abpromise guarantee covers the use of ab127756 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 73 kDa.

Target

  • Function

    Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination.
  • Sequence similarities

    Contains 1 SH3 domain.
    Contains 1 UBA domain.
  • Cellular localization

    Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • Cbl interacting protein p70 antibody
    • Cbl interacting protein Sts 1 antibody
    • Cbl interacting protein Sts1 antibody
    • Cbl-interacting protein p70 antibody
    • KIAA1959 antibody
    • MGC15437 antibody
    • Nm23 phosphorylated unknown substrate antibody
    • p70 antibody
    • SH3 domain containing 70 kDa protein antibody
    • Sts 1 antibody
    • STS-1 antibody
    • STS1 antibody
    • Suppressor of T cell receptor signaling 1 antibody
    • Suppressor of T-cell receptor signaling 1 antibody
    • T-cell ubiquitin ligand 2 antibody
    • TULA-2 antibody
    • Tyrosine-protein phosphatase STS1/TULA2 antibody
    • Ubash3b antibody
    • Ubiquitin associated and SH3 domain containing B antibody
    • Ubiquitin-associated and SH3 domain-containing protein B antibody
    • UBS3B_HUMAN antibody
    see all

Images

  • All lanes : Anti-Sts1 antibody (ab127756) at 1/1000 dilution

    Lane 1 : A431 whole cell lysate
    Lane 2 : Jurkat whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 73 kDa



    7.5% SDS PAGE

References

ab127756 has not yet been referenced specifically in any publications.

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