Overview

  • Product name

    Anti-Sts1 antibody - C-terminal
    See all Sts1 primary antibodies
  • Description

    Rabbit polyclonal to Sts1 - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IFmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Rhesus monkey
  • Immunogen

    Recombinant fragment within Human Sts1 (C terminal). The exact sequence is proprietary.
    Database link: Q8TF42

  • Positive control

    • ICC/IF: A431 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab228988 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/100 - 1/1000.

Target

  • Function

    Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination.
  • Sequence similarities

    Contains 1 SH3 domain.
    Contains 1 UBA domain.
  • Cellular localization

    Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • Cbl interacting protein p70 antibody
    • Cbl interacting protein Sts 1 antibody
    • Cbl interacting protein Sts1 antibody
    • Cbl-interacting protein p70 antibody
    • KIAA1959 antibody
    • MGC15437 antibody
    • Nm23 phosphorylated unknown substrate antibody
    • p70 antibody
    • SH3 domain containing 70 kDa protein antibody
    • Sts 1 antibody
    • STS-1 antibody
    • STS1 antibody
    • Suppressor of T cell receptor signaling 1 antibody
    • Suppressor of T-cell receptor signaling 1 antibody
    • T-cell ubiquitin ligand 2 antibody
    • TULA-2 antibody
    • Tyrosine-protein phosphatase STS1/TULA2 antibody
    • Ubash3b antibody
    • Ubiquitin associated and SH3 domain containing B antibody
    • Ubiquitin-associated and SH3 domain-containing protein B antibody
    • UBS3B_HUMAN antibody
    see all

Images

  • Paraformaldehyde-fixed A431 (human epidermoid carcinoma cell line) cells stained for Sts1 (green) using ab228988 at 1/500 dilution in ICC/IF. Counterstains: Hoechst 33342 (blue) and alpha tubulin filaments (red).

References

ab228988 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab228988.
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