Overview

  • Product name

    Substance P (7-11), Substance P fragment
  • Description

    Substance P fragmen. Increases PGE2 and collagenase production.
  • Biological description

    Substance P fragment. Increases PGE2 and collagenase production. Involved in pain signal transmission. Anti-inflammatory and immunomodulatory agent. Active in vitro and in vivo. Substance P available (ab120170).
  • Purity

    > 95%
  • CAS Number

    51165-05-0
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Nieuwmeyer F  et al. Ava[L-Pro9,N-MeLeu10] substance P(7-11) (GR 73632) and Sar9, Met(O2)11 increase distention-induced peristalsis through activation of neurokinin-1 receptors on smooth muscle and interstitial cells of cajal. J Pharmacol Exp Ther 317:439-45 (2006). Read more (PubMed: 16330493) »
  • De Araújo JE  et al. Anxiogenic effects of substance P and its 7-11 C terminal, but not the 1-7 N terminal, injected into the dorsal periaqueductal gray. Peptides 20:1437-43 (1999). Read more (PubMed: 10698119) »
  • Halliday DA  et al. The substance P fragment SP-(7-11) increases prostaglandin E2, intracellular Ca2+ and collagenase production in bovine articular chondrocytes. Biochem J 292 ( Pt 1):57-62 (1993). Read more (PubMed: 7684899) »

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