Product nameSuccinylcholine chloride dihydrate, Nicotinic AChR agonist
DescriptionNicotinic AChR agonist, also acts as a depolarizing neuromuscular blocker.
- Bis(trimethylammonioethyl) succinate chloride
- Succinyldicholine dichloride
- Suxamethonium chloride dihydrate
Cholinergic antagonist which induces a long-lasting depolarization of the acetylcholine neuron membrane; neuromuscular blocking agent.
Chemical name2,2-[(1,4-Dioxo-1,4-butanediyl)bis(oxy)]bis(N,N,N-trimethylethanaminium) chloride dihydrate
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 2 mM and in water to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This product has been referenced in:
- Limapichat W et al. Chemical scale studies of the Phe-Pro conserved motif in the cys loop of Cys loop receptors. J Biol Chem 285:8976-84 (2010). Read more (PubMed: 20068044) »
- Martyn JA & Richtsfeld M Succinylcholine-induced hyperkalemia in acquired pathologic states: etiologic factors and molecular mechanisms. Anesthesiology 104:158-69 (2006). Read more (PubMed: 16394702) »
- Delvaux H et al. Relative efficiency of succinylcholine, xylazine, and carfentanil/xylazine mixtures to immobilize free-ranging moose. J Wildl Dis 35:38-48 (1999). Read more (PubMed: 10073344) »
- Abernethy MH et al. A new succinylcholine-based assay of plasma cholinesterase. Clin Chem 30:192-5 (1984). Read more (PubMed: 6362911) »