Anti-SUCLG2 antibody (ab96172)

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Overview

  • Product name

    Anti-SUCLG2 antibody
    See all SUCLG2 primary antibodies

  • Description

    Rabbit polyclonal to SUCLG2

  • Host species

    Rabbit

  • Tested applications

    Suitable for: WBmore details

  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow

  • Immunogen

    Recombinant fragment, corresponding to a region within the N terminal amino acids 1-204 of Human SUCLG2.

  • Positive control

    • 293T, A431, H1299, HeLa S3, HepG2, MOLT4 or Raji cell lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab96172 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 47 kDa.

Target

  • Function

    Catalyzes the GTP-dependent ligation of succinate and CoA to form succinyl-CoA.

  • Tissue specificity

    Mainly expressed in liver, kidney, heart, spleen and skeletal muscle. Also found in intestine and colon, and in low amounts in lung, brain, prostate, testis and ovary.

  • Pathway

    Carbohydrate metabolism; tricarboxylic acid cycle.

  • Sequence similarities

    Belongs to the succinate/malate CoA ligase beta subunit family.
    Contains 1 ATP-grasp domain.

  • Cellular localization

    Mitochondrion.
  • Information by UniProt

  • Database links

    see all

  • Alternative names

    • EC 6.2.1.4 antibody
    • G BETA antibody
    • GBETA antibody
    • GTP specific succinyl-CoA synthetase beta subunit antibody
    • GTP specific succinyl-CoA synthetase subunit beta antibody
    • GTP-specific succinyl-CoA synthetase subunit beta antibody
    • mitochondrial antibody
    • SCS betaG antibody
    • SCS-betaG antibody
    • SUCB2_HUMAN antibody
    • Succinate CoA ligase GDP forming beta subunit antibody
    • Succinate-Coenzyme A ligase, GDP-forming, beta subunit antibody
    • Succinyl CoA ligase GDP forming beta chain mitochondrial antibody
    • Succinyl CoA synthetase betaG chain antibody
    • Succinyl-CoA ligase [GDP-forming] subunit beta antibody
    • Succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial antibody
    • Succinyl-CoA synthetase beta-G chain antibody
    • SUCLG2 antibody
    see all

Images

  • Western blot - Anti-SUCLG2 antibody (ab96172)
    Western blot - Anti-SUCLG2 antibody (ab96172)
    All lanes : Anti-SUCLG2 antibody (ab96172) at 1/1000 dilution

    Lane 1 : 293T whole cell lysate
    Lane 2 : A431 whole cell lysate
    Lane 3 : H1299 whole cell lysate
    Lane 4 : HeLa S3 whole cell lysate
    Lane 5 : Hep G2 whole cell lysate
    Lane 6 : MOLT4 whole cell lysate
    Lane 7 : Raji whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 47 kDa



    10% SDS PAGE

References

This product has been referenced in:

  • Zhang W  et al. Ketamine exerts a protective role in a cell-based model of major depressive disorder via the inhibition of apoptosis and inflammation and activation of the Krebs cycle. Bosn J Basic Med Sci N/A:N/A (2019). Read more (PubMed: 31215856) »
  • Dobolyi A  et al. Exclusive neuronal expression of SUCLA2 in the human brain. Brain Struct Funct 220:135-51 (2015). Read more (PubMed: 24085565) »
See all 2 Publications for this product

Publishing research using ab96172? Please let us know so that we can cite the reference in this datasheet.

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