Anti-SUCLG2 antibody (ab96172)
Key features and details
- Rabbit polyclonal to SUCLG2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-SUCLG2 antibody
See all SUCLG2 primary antibodies -
Description
Rabbit polyclonal to SUCLG2 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Cow
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Immunogen
Recombinant fragment, corresponding to a region within the N terminal amino acids 1-204 of Human SUCLG2.
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Positive control
- 293T, A431, H1299, HeLa S3, HepG2, MOLT4 or Raji cell lysates
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab96172 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 47 kDa.
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| Notes |
|---|
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WB
1/500 - 1/3000. Predicted molecular weight: 47 kDa. |
Target
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Function
Catalyzes the GTP-dependent ligation of succinate and CoA to form succinyl-CoA. -
Tissue specificity
Mainly expressed in liver, kidney, heart, spleen and skeletal muscle. Also found in intestine and colon, and in low amounts in lung, brain, prostate, testis and ovary. -
Pathway
Carbohydrate metabolism; tricarboxylic acid cycle. -
Sequence similarities
Belongs to the succinate/malate CoA ligase beta subunit family.
Contains 1 ATP-grasp domain. -
Cellular localization
Mitochondrion. - Information by UniProt
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Database links
- Entrez Gene: 537713 Cow
- Entrez Gene: 8801 Human
- Entrez Gene: 20917 Mouse
- Entrez Gene: 362404 Rat
- Omim: 603922 Human
- SwissProt: Q3MHX5 Cow
- SwissProt: Q96I99 Human
- SwissProt: Q9Z2I8 Mouse
see all -
Alternative names
- EC 6.2.1.4 antibody
- G BETA antibody
- GBETA antibody
see all
Images
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Western blot - Anti-SUCLG2 antibody (ab96172)All lanes : Anti-SUCLG2 antibody (ab96172) at 1/1000 dilution
Lane 1 : 293T whole cell lysate
Lane 2 : A431 whole cell lysate
Lane 3 : H1299 whole cell lysate
Lane 4 : HeLa S3 whole cell lysate
Lane 5 : Hep G2 whole cell lysate
Lane 6 : MOLT4 whole cell lysate
Lane 7 : Raji whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 47 kDa
10% SDS PAGE
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab96172 has been referenced in 2 publications.
- Zhang W et al. Ketamine exerts a protective role in a cell-based model of major depressive disorder via the inhibition of apoptosis and inflammation and activation of the Krebs cycle. Bosn J Basic Med Sci N/A:N/A (2019). PubMed: 31215856
- Dobolyi A et al. Exclusive neuronal expression of SUCLA2 in the human brain. Brain Struct Funct 220:135-51 (2015). PubMed: 24085565