Overview

  • Product name

    Sulfadoxine, sulfonamide antibiotic
  • Description

    Highly long-lasting sulfonamide antibiotic
  • Biological description

    Highly long-lasting sulfonamide antibiotic. Blocks dihydrofolic acid synthesis. Inhibits dihydropteroate synthase. Competitive bacterial PABA inhibitor. Shows antiplasmodial effects in in vivo. Orally active.
  • CAS Number

    2447-57-6
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Combrinck JM  et al. Insights into the role of heme in the mechanism of action of antimalarials. ACS Chem Biol 8:133-7 (2013). Read more (PubMed: 23043646) »
  • Zakai HA  et al. Prevalence of mutation and phenotypic expression associated with sulfadoxine-pyrimethamine resistance in Plasmodium falciparum and Plasmodium vivax. Folia Parasitol (Praha) 60:372-6 (2013). Read more (PubMed: 24261139) »
  • Dapper DV  et al. Antiplasmodial effects of the aqueous extract of Phyllantus amarus Schumach and Thonn against Plasmodium berghei in Swiss albino mice. Niger J Physiol Sci 22:19-25 (0). Read more (PubMed: 18379613) »

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