Sulfo-NHS (sulfo-N-hydroxysuccinimide), Carboxylate-primary amine chemical modification reagent (ab145608)

Overview

  • Product name

    Sulfo-NHS (sulfo-N-hydroxysuccinimide), Carboxylate-primary amine chemical modification reagent
  • Description

    Carboxylate-primary amine chemical modification reagent
  • Biological description

    Carboxylate-primary amine chemical modification reagent. Converts carboxyl groups to amine-reactive NHS esters for bioconjugation, crosslinking, labeling and immobilization methods. Increases the efficiency of EDC-mediated coupling reactions.
  • Purity

    > 95%
  • CAS Number

    106627-54-7
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    1-Hydroxy-2,5-dioxopyrrolidine-3-sulfonate sodium salt
  • Molecular weight

    217.13
  • Molecular formula

    C4H4NNaO6S
  • PubChem identifier

    3520574
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 5 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1C(C(=O)N(C1=O)O)S(=O)(=O)[O-].[Na+]
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Alegria-Schaffer A General protein-protein cross-linking. Methods Enzymol 539:81-7 (2014). Read more (PubMed: 24581440) »
  • App C  et al. Peptide labeling with photoactivatable trifunctional cadaverine derivative and identification of interacting partners by biotin transfer. Anal Biochem 456:14-21 (2014). Read more (PubMed: 24732115) »
  • Bartczak D & Kanaras AG Preparation of peptide-functionalized gold nanoparticles using one pot EDC/sulfo-NHS coupling. Langmuir 27:10119-23 (2011). Read more (PubMed: 21728291) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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