Product nameSulfobetaine 12, Zwitterionic detergent
DescriptionZwitterionic detergent which retains its zwitterionic character over a broad pH range.
- Zwittergent 3-12
Synthetic zwitterionic detergent, which unlike other amphoteric surfactants, retains its zwitterionic character over a broad pH range. This property is attributed to the presence of both a strongly basic quaternary ammonium ion and an acidic sulfonate ion of equal strength. This ionic balance presumably prevents irreversible binding to either anionic or cationic compounds.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This product has been referenced in:
- Raper SE et al. Identification and partial characterization of a somatostatin-14 binding protein on rat liver plasma membranes. Hepatology 16:433-9 (1992). Read more (PubMed: 1353473) »
- Nollstadt KH et al. Potential of the sulfobetaine detergent Zwittergent 3-12 as a desorbing agent in biospecific and bioselective affinity chromatography. J Chromatogr 497:87-100 (1989). Read more (PubMed: 2625482) »
- Byers S et al. The effect of zwitterionic detergents on the extraction and functional properties of cartilage proteoglycans. J Biol Chem 262:9166-74 (1987). Read more (PubMed: 3597409) »