Key features and details
- Non-steroidal anti-inflammatory agent
- CAS Number: 38194-50-2
- Purity: > 98%
- Soluble in DMSO to 100 mM and ethanol to 25 mM
- Form / State: Solid
- Source: Synthetic
Product nameSulindac, non-steroidal anti-inflammatory agent
DescriptionNon-steroidal anti-inflammatory agent
A NSAID analgesic prodrug. Inhibits cyclooxgenase and cyclic-GMP phosphodiesterase (cGMP-PDE). Induces apoptosis in tumor cells. Active in vivo and in vitro. Orally active.
Chemical name2-[6-Fluoro-2-methyl-3-[(4-methylsulfinylphenyl)methylidene]inden-1-yl] acetic acid
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM and ethanol to 25 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab142950 has been referenced in 1 publication.
- Pritchard R et al. Celecoxib inhibits mitochondrial O2 consumption, promoting ROS dependent death of murine and human metastatic cancer cells via the apoptotic signalling pathway. Biochem Pharmacol 154:318-334 (2018). PubMed: 29800556