Overview

  • Product name

    Sulindac sulfide, COX-1 and 2 inhibitor
  • Description

    Active metabolite of Sulindac. COX-1 and 2 inhibitor.
  • Biological description

    Cell-permeable, active metabolite of Sulindac. Inhibits Ras-induced malignant transformation and Ras/Raf-dependent transactivation. COX-1 and 2 inhibitor (Ki values are 1.02 and 10.43 μM, respectively). Additionally, inhibits γ-secretase. Apoptosis inducer.
  • Purity

    > 98%
  • CAS Number

    32004-67-4
  • Chemical structure

    Chemical Structure

Properties

References

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