Overview

  • Product name

  • Description

    Rabbit polyclonal to SULT1B1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Rat, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide within residues: LSPKDILRKD LKLVHGYPMT CAFASNWEKI EQFHSRPDDI VIATYPKSGT , corresponding to N terminal amino acids 2-51 of Human SULT1B1 (NP_055280)

  • Positive control

    • Human fetal intestine lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab89707 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 35 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function

    Catalyzes the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3,3'-diiodothyronine, triidothyronine, reverse triiodothyronine and thyroxine.
  • Tissue specificity

    Highly expressed in the liver, peripheral blood leukocytes, colon (mucosal lining), small intestine (jejunum) and spleen. A lesser expression was observed in the lung, placenta and thymus.
  • Sequence similarities

    Belongs to the sulfotransferase 1 family.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • Dopa/tyrosine sulfotransferase antibody
    • MGC13356 antibody
    • ST1B1 antibody
    • ST1B1_HUMAN antibody
    • ST1B2 antibody
    • Sulfotransferase 1B1 antibody
    • Sulfotransferase 1B2 antibody
    • Sulfotransferase family 1B member 1 antibody
    • Sulfotransferase family cytosolic 1B member 1 antibody
    • SULT1B1 antibody
    • SULT1B2 antibody
    • Thyroid hormone sulfotransferase antibody
    see all

Images

  • Anti-SULT1B1 antibody (ab89707) at 1 µg/ml + human fetal intestine lysate at 10 µg

    Secondary
    anti-Rabbit IgG HRP at 1/50000 dilution

    Predicted band size: 35 kDa
    Observed band size: 35 kDa

References

This product has been referenced in:

  • Probert PM  et al. Progenitor-derived hepatocyte-like (B-13/H) cells metabolise 1'-hydroxyestragole to a genotoxic species via a SULT2B1-dependent mechanism. Toxicol Lett 243:98-110 (2016). WB . Read more (PubMed: 26739637) »
See 1 Publication for this product

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