Product nameAnti-Superoxide Dismutase 3 / EC-SOD antibody [EPR10860]
See all Superoxide Dismutase 3 / EC-SOD primary antibodies
DescriptionRabbit monoclonal [EPR10860] to Superoxide Dismutase 3 / EC-SOD
Tested applicationsSuitable for: WB, IHC-Pmore details
Unsuitable for: ICC/IF or IP
Species reactivityReacts with: Human
Does not react with: Mouse, Rat
within Human Superoxide Dismutase 3/ EC-SOD aa 200 to the C-terminus (Cysteine residue). The exact sequence is proprietary.
Database link: P08294
- Human fetal lung and heart lysates; Human heart and kidney tissues.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
PurityTissue culture supernatant
Our Abpromise guarantee covers the use of ab171738 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000 - 1/5000. Predicted molecular weight: 26 kDa.|
|IHC-P||1/50 - 1/100.|
FunctionProtect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen.
Tissue specificityExpressed in blood vessels, heart, lung, kidney and placenta. Major SOD isoenzyme in extracellular fluids such as plasma, lymph and synovial fluid.
Sequence similaritiesBelongs to the Cu-Zn superoxide dismutase family.
Cellular localizationSecreted > extracellular space. 99% of EC-SOD is anchored to heparan sulfate proteoglycans in the tissue interstitium, and 1% is located in the vasculature in equilibrium between the plasma and the endothelium.
- Information by UniProt
- EC SOD antibody
- EC-SOD antibody
- Extracellular superoxide dismutase [Cu Zn] antibody
Immunohistochemistry of paraffin-embedded Human kidney tissue labeling Superoxide Dismutase 3 / EC-SOD using ab171738 at 1/50 dilution.
Immunohistochemistry of paraffin-embedded Human heart tissue labeling Superoxide Dismutase 3 / EC-SOD using ab171738 at 1/50 dilution.
All lanes : Anti-Superoxide Dismutase 3 / EC-SOD antibody [EPR10860] (ab171738) at 1/1000 dilution
Lane 1 : Human fetal lung lysate
Lane 2 : Human fetal heart lysate
Lysates/proteins at 10 µg per lane.
Predicted band size: 26 kDa
This product has been referenced in:
- Bodega G et al. The Antioxidant Machinery of Young and Senescent Human Umbilical Vein Endothelial Cells and Their Microvesicles. Oxid Med Cell Longev 2017:7094781 (2017). WB ; Human . Read more (PubMed: 28642812) »
- Kim CH Expression of extracellular superoxide dismutase protein in diabetes. Arch Plast Surg 40:517-21 (2013). WB, IHC-P ; Human . Read more (PubMed: 24086803) »