Product nameAnti-Surfactant protein D / SP-D antibody [VI F11]
See all Surfactant protein D / SP-D primary antibodies
DescriptionMouse monoclonal [VI F11] to Surfactant protein D / SP-D
SpecificityAlveolar type III cells stain negative. No reaction on rat skin, colon, kidney and liver.
Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
Species reactivityReacts with: Rat, Human
Full length native protein (purified) corresponding to Rat Surfactant protein D/ SP-D. Purified from bronchoalveolar lavage.
EpitopeThe VIF11 epitope is localized in the lectin domain of Surfactant protein D / SP-D.
- Alveolar type II cells, alveolar macrophages, two types of Clara cells SP-A+ and SP-A-.
Previously labelled as Surfactant protein D.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.01% Thimerosal (merthiolate)
Constituent: 1% BSA
Concentration information loading...
PurityProtein G purified
Clone numberVI F11
Light chain typekappa
Our Abpromise guarantee covers the use of ab15688 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-P: 1/20 (human) - 1/400 (rat).
WB: Use at an assay dependent dilution. Predicted molecular weight: 43 kDa.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionContributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
Sequence similaritiesBelongs to the SFTPD family.
Contains 1 C-type lectin domain.
Contains 1 collagen-like domain.
modificationsThe N-terminus is blocked.
Hydroxylation on proline residues within the sequence motif, GXPG, is most likely to be 4-hydroxy as this fits the requirement for 4-hydroxylation in vertebrates.
Cellular localizationSecreted > extracellular space > extracellular matrix. Secreted > extracellular space > surface film.
- Information by UniProt
- COLEC 7 antibody
- COLEC7 antibody
- Collectin-7 antibody
This product has been referenced in:
- Yadav AK et al. Differential expression of collectins in human placenta and role in inflammation during spontaneous labor. PLoS One 9:e108815 (2014). WB ; Human . Read more (PubMed: 25303045) »
- Kasper M et al. Monoclonal antibodies to surfactant protein D: evaluation of immunoreactivity in normal rat lung and in a radiation-induced fibrosis model. Exp Lung Res 21:577-88 (1995). Read more (PubMed: 7588444) »