Overview

  • Product name

    Anti-Surfactant protein D/SP-D antibody [1.7]
    See all Surfactant protein D/SP-D primary antibodies
  • Description

    Mouse monoclonal [1.7] to Surfactant protein D/SP-D
  • Host species

    Mouse
  • Tested applications

    Suitable for: WB, IHC-P, IHC-Fr, ICC/IFmore details
  • Species reactivity

    Reacts with: Pig
  • Immunogen

    Tissue, cells or virus corresponding to Pig Surfactant protein D/SP-D. Surfactant D from porcine lung.
    Database link: Q9N1X4

  • Positive control

    • Pig lung tissue.
  • General notes

    Previously labelled as Surfactant protein D.

Properties

Applications

Our Abpromise guarantee covers the use of ab194859 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Detects a band of approximately 138 kDa (predicted molecular weight: 38 kDa).
IHC-P Use at an assay dependent concentration. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

TRIS/EDTA buffer pH8.0 is recommended for this purpose.

IHC-Fr Use a concentration of 1 µg/ml.
ICC/IF Use at an assay dependent concentration.

Target

  • Function

    Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
  • Sequence similarities

    Belongs to the SFTPD family.
    Contains 1 C-type lectin domain.
    Contains 1 collagen-like domain.
  • Post-translational
    modifications

    The N-terminus is blocked.
    Hydroxylation on proline residues within the sequence motif, GXPG, is most likely to be 4-hydroxy as this fits the requirement for 4-hydroxylation in vertebrates.
  • Cellular localization

    Secreted > extracellular space > extracellular matrix. Secreted > extracellular space > surface film.
  • Information by UniProt
  • Database links

  • Alternative names

    • COLEC 7 antibody
    • COLEC7 antibody
    • Collectin-7 antibody
    • Collectin7 antibody
    • Lung surfactant protein D antibody
    • PSP D antibody
    • PSP-D antibody
    • PSP-D Surfactant protein D antibody
    • PSPD antibody
    • Pulmonary surfactant apoprotein antibody
    • Pulmonary surfactant associated protein D antibody
    • Pulmonary surfactant associated protein PSP-D antibody
    • Pulmonary surfactant-associated protein D antibody
    • SFTP 4 antibody
    • SFTP4 antibody
    • SFTPD antibody
    • SFTPD_HUMAN antibody
    • SP D antibody
    • SP-D antibody
    • Surfactant associated protein pulmonary 4 antibody
    • Surfactant protein D antibody
    • Surfactant pulmonary associated protein D antibody
    see all

Images

  • Immunohistochemical analysis of frozen pig lung tissue labeling Surfactant protein D/SP-D with ab194859 at 1 µg/ml.

References

ab194859 has not yet been referenced specifically in any publications.

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