Overview

  • Product name

    Anti-Surfactant protein D/SP-D antibody
    See all Surfactant protein D/SP-D primary antibodies
  • Description

    Rabbit polyclonal to Surfactant protein D/SP-D
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human Surfactant protein D/SP-D aa 340-370 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    GEPNDDGGSED CVEIFTNGKW NDRACGEKRL


    Database link: P35247

  • Positive control

    • Rat lung lysate; Human lung carcinoma lysate; Rat and mouse lung and human lung carcinoma tissues.
  • General notes

    Previously labelled as Surfactant protein D.

Properties

Applications

Our Abpromise guarantee covers the use of ab203309 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/100 - 1/1000. Detects a band of approximately 38, 41 kDa (predicted molecular weight: 38 kDa).

Target

  • Function

    Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
  • Sequence similarities

    Belongs to the SFTPD family.
    Contains 1 C-type lectin domain.
    Contains 1 collagen-like domain.
  • Post-translational
    modifications

    The N-terminus is blocked.
    Hydroxylation on proline residues within the sequence motif, GXPG, is most likely to be 4-hydroxy as this fits the requirement for 4-hydroxylation in vertebrates.
  • Cellular localization

    Secreted > extracellular space > extracellular matrix. Secreted > extracellular space > surface film.
  • Information by UniProt
  • Database links

  • Alternative names

    • COLEC 7 antibody
    • COLEC7 antibody
    • Collectin-7 antibody
    • Collectin7 antibody
    • Lung surfactant protein D antibody
    • PSP D antibody
    • PSP-D antibody
    • PSP-D Surfactant protein D antibody
    • PSPD antibody
    • Pulmonary surfactant apoprotein antibody
    • Pulmonary surfactant associated protein D antibody
    • Pulmonary surfactant associated protein PSP-D antibody
    • Pulmonary surfactant-associated protein D antibody
    • SFTP 4 antibody
    • SFTP4 antibody
    • SFTPD antibody
    • SFTPD_HUMAN antibody
    • SP D antibody
    • SP-D antibody
    • Surfactant associated protein pulmonary 4 antibody
    • Surfactant protein D antibody
    • Surfactant pulmonary associated protein D antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Mouse lung tissue labeling Surfactant protein D/SP-D with ab203309 at 1/2000 dilution followed by conjugation to the secondary antibody and DAB staining.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human lung carcinoma tissue labeling Surfactant protein D/SP-D with ab203309 at 1/200 dilution followed by conjugation to the secondary antibody and DAB staining.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Rat lung tissue labeling Surfactant protein D/SP-D with ab203309 at 1/200 dilution followed by conjugation to the secondary antibody and DAB staining.

  • All lanes : Anti-Surfactant protein D/SP-D antibody (ab203309) at 1/200 dilution

    Lane 1 : Rat lung lysate
    Lane 2 : human lung carcinoma lysate

    Secondary
    All lanes : Goat Anti-Rabbit IgG Antibody (H+L), HRP at 1/3000 dilution

    Predicted band size: 38 kDa

References

ab203309 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab203309.
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