Key features and details
- Mouse monoclonal [SPDE] to Surfactant protein D/SP-D
- Suitable for: IHC-P, WB
- Reacts with: Rat, Human
- Isotype: IgG2b
Product nameAnti-Surfactant protein D/SP-D antibody [SPDE]
See all Surfactant protein D/SP-D primary antibodies
DescriptionMouse monoclonal [SPDE] to Surfactant protein D/SP-D
Rat: ab15687 recognizes a conformational epitope of Surfactant protein D/SP-D Other Species: Positive on human tissues.
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Rat, Human
Full length native protein (purified) corresponding to Rat Surfactant protein D/SP-D. Purified from bronchoalveolar lavage.
Previously labelled as Surfactant protein D.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.1% Sodium azide
Constituents: PBS, 0.5% BSA
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab15687 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/50 - 1/100.|
|WB||Use at an assay dependent concentration. Predicted molecular weight: 43 kDa.|
FunctionContributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
Sequence similaritiesBelongs to the SFTPD family.
Contains 1 C-type lectin domain.
Contains 1 collagen-like domain.
modificationsThe N-terminus is blocked.
Hydroxylation on proline residues within the sequence motif, GXPG, is most likely to be 4-hydroxy as this fits the requirement for 4-hydroxylation in vertebrates.
Cellular localizationSecreted > extracellular space > extracellular matrix. Secreted > extracellular space > surface film.
- Information by UniProt
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ab15687 has been referenced in 3 publications.
- Demas DM et al. Glutamine Metabolism Drives Growth in Advanced Hormone Receptor Positive Breast Cancer. Front Oncol 9:686 (2019). PubMed: 31428575
- Wu NC et al. Intravenous superoxide dismutase as a protective agent to prevent impairment of lung function induced by high tidal volume ventilation. BMC Pulm Med 17:105 (2017). PubMed: 28747201
- Madsen C et al. Small molecule inhibitors of Ago2 decrease Venezuelan equine encephalitis virus replication. Antiviral Res 112:26-37 (2014). PubMed: 25448087