Key features and details
- Rabbit polyclonal to SUV3L1
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
Product nameAnti-SUV3L1 antibody
See all SUV3L1 primary antibodies
DescriptionRabbit polyclonal to SUV3L1
Tested applicationsSuitable for: WB, ICC/IFmore details
Species reactivityReacts with: Human
Recombinant fragment, corresponding to a region within C terminal amino acids 545-739 of Human SUV3L1 (Q8IYB8).
- PC3 whole cell lysate; HeLa cells.
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Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab127909 is purified by antigen-affinity chromatography.
Our Abpromise guarantee covers the use of ab127909 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 88 kDa.|
|ICC/IF||1/100 - 1/1000.|
FunctionMajor helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.
Tissue specificityBroadly expressed.
Sequence similaritiesBelongs to the helicase family.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase C-terminal domain.
Cellular localizationNucleus. Mitochondrion matrix. Mitochondrion matrix > mitochondrion nucleoid.
- Information by UniProt
- 6330443E10Rik antibody
- ATP dependent RNA helicase SUPV3L1, mitochondrial antibody
- ATP-dependent RNA helicase SUPV3L1 antibody
Anti-SUV3L1 antibody (ab127909) at 1/1000 dilution + PC3 whole cell lysate at 30 µg
Developed using the ECL technique.
Predicted band size: 88 kDa
7.5% SDS PAGE
ab127909 at 1/500 dilution staining SUV3L1 in methanol-fixed HeLa cells by confocal Immunofluorescence. Alpha-tubulin filaments are stained in red.
ab127909 has not yet been referenced specifically in any publications.