Key features and details
- Rabbit polyclonal to SUV420h1
- Reacts with: Human
- Isotype: IgG
Product nameAnti-SUV420h1 antibody
See all SUV420h1 primary antibodies
DescriptionRabbit polyclonal to SUV420h1
Species reactivityReacts with: Human
Predicted to work with: Mouse
Synthetic peptides derived from internal domains of Human SUV420h1.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferConstituent: Whole serum
Concentration information loading...
FunctionHistone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5B is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) (By similarity). Plays a role in myogenesis by regulating the expression of target genes, such as EID3.
Sequence similaritiesBelongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.
Contains 1 SET domain.
Cellular localizationNucleus. Chromosome. Associated with pericentric heterochromatin. CBX1 and CBX5 are required for the localization to pericentric heterochromatin (By similarity).
- Information by UniProt
- CGI 85 antibody
- CGI85 antibody
- Histone-lysine N-methyltransferase KMT5B antibody
ab104875 has not yet been referenced specifically in any publications.