Overview

  • Product name

    Anti-SVCT1 antibody
  • Description

    Rabbit polyclonal to SVCT1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Recombinant fragment corresponding to Human SVCT1 aa 173-259.
    Database link: Q9UHI7

  • Positive control

    • WB: A549 whole cell lysate; Mouse kidney and liver tissue lysate. IHC-P: Human small intestine tissue. ICC/IF: A549 cells.
  • General notes

    Previously labelled as SLC23A1.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.4
    Preservative: 0.03% Proclin
    Constituents: 50% Glycerol, PBS
  • Concentration information loading...
  • Purity

    Protein G purified
  • Purification notes

    Purity >95%.
  • Clonality

    Polyclonal
  • Isotype

    IgG

Applications

Our Abpromise guarantee covers the use of ab236878 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000.
IHC-P 1/20 - 1/200.
ICC/IF 1/50 - 1/200.

Target

  • Function

    Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate.
  • Tissue specificity

    Highly expressed in adult small intestine, kidney, thymus, ovary, colon, prostate and liver, and in fetal kidney, liver and thymus.
  • Sequence similarities

    Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily.
  • Post-translational
    modifications

    Phosphorylated.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • hSVCT1 antibody
    • Na(+)/L-ascorbic acid transporter 1 antibody
    • S23A1_HUMAN antibody
    • Slc23a1 antibody
    • Sodium-dependent vitamin C transporter 1 antibody
    • solute carrier family 23 (nucleobase transporters), member 1 antibody
    • Solute carrier family 23 member 1 antibody
    • SVCT1 antibody
    • Yolk sac permease-like molecule 3 antibody
    • YSPL3 antibody
    see all

Images

  • All lanes : Anti-SVCT1 antibody (ab236878) at 1/500 dilution

    Lane 1 : A549 (Human lung carcinoma cell line) whole cell lysate
    Lane 2 : Mouse liver tissue lysate
    Lane 3 : Mouse kidney tissue lysate

    Secondary
    All lanes : Goat polyclonal to Rabbit IgG at 1/10000 dilution
  • Paraffin-embedded human small intestine tissue stained for SVCT1 with ab236878 at a 1/100 dilution in immunohistochemical analysis.

  • A549 (Human lung carcinoma cell line) cells stained for SVCT1 (Green) using ab236878 at a 1/100 dilution in ICC/IF. Secondary used is an Alexa-Fluor®488-conjugated Goat Anti-Rabbit IgG (H+L).

References

ab236878 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab236878.
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