Anti-SYCE1 antibody (ab122634)

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Product name

Anti-SYCE1 antibody
See all SYCE1 primary antibodies
Description

Rabbit polyclonal to SYCE1
Host species

Rabbit
Tested applications

Suitable for: IHC-P, WBmore details
Species reactivity

Reacts with: Human
Immunogen

antigen sequence: QQQQQKRQRL KEELEKHGMQ VPAQAQSTQE EEAGPGDVAS PKPLKGERPG AAHQAGPDVL IGQEDTLHPD LSPRGFQEIK EL, corresponding to amino acids 269-350 of Human SYCE1.

Run BLAST with Run BLAST with
Positive control
- Human duodenum tissue; RT 4, U 251 MG, Human liver lysates.

Form

Liquid
Storage instructions

Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle. Store undiluted.
Storage buffer

pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol
Concentration information loading...
Purity

Immunogen affinity purified
Clonality

Polyclonal
Isotype

IgG
Research areas

Our Abpromise guarantee covers the use of ab122634 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application	Abreviews	Notes
IHC-P		1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB		1/250 - 1/500.

Function

Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Requires SYCP1 in order to be incorporated into the central element. May have a role in the synaptonemal complexe assembly, stabilization and recombination.
Sequence similarities

Belongs to the SYCE family.
Cellular localization

Nucleus. Chromosome. Associates with chromatin. In prophase I stage of meiosis, localizes in the transverse central elements of the central region between lateral elements of the synaptonemal complexes. Found only where the chromosome cores are synapsed. Colocalizes with SYCE2 in the central elements.
Target information above from: UniProt accession Q8N0S2 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
Database links
- Entrez Gene: 93426 Human
- Omim: 611486 Human
- SwissProt: Q8N0S2 Human
- Unigene: 553795 Human
Alternative names
- bA108K14.6 antibody
- C10orf94 antibody
- Cancer/testis antigen 76 antibody
- CT76 antibody
- RP11-108K14.6 antibody
- Syce1 antibody
- SYCE1_HUMAN antibody
- Synaptonemal complex central element protein 1 antibody
see all

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SYCE1 antibody (ab122634)

ab122634 at 1/200 dilution staining SYCE1 in Paraffin-embedded Human duodenum tissue by Immunohistochemistry.
Western blot - Anti-SYCE1 antibody (ab122634)

All lanes : Anti-SYCE1 antibody (ab122634) at 1/250 dilution

Lane 1 : RT 4 lysate
Lane 2 : U 251 MG lysate
Lane 3 : Human plasma lysate
Lane 4 : Human liver lysate
Lane 5 : Human tonsil lysate

Developed using the ECL technique.

ab122634 has not yet been referenced specifically in any publications.

Publishing research using ab122634? Please let us know so that we can cite the reference in this datasheet.

Customer reviews and Q&As

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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