Overview

  • Product name

    Anti-SYN4 antibody [EPR8707]
    See all SYN4 primary antibodies
  • Description

    Rabbit monoclonal [EPR8707] to SYN4
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: IHC-P or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human SYN4 aa 1-100. The exact sequence is proprietary.

  • Positive control

    • Mouse brain, Rat brain and Human fetal brain lysates.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab133767 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 50 kDa (predicted molecular weight: 58 kDa).
  • Application notes
    Is unsuitable for IHC-P or IP.
  • Target

    • Function

      Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex (By similarity). May participate in regulating the subcellular location of diacylglycerol kinase-zeta to ensure that diacylglycerol is rapidly inactivated following receptor activation.
    • Tissue specificity

      Brain specific. In CNS, it is expressed in the perikaryon and proximal portion of the neuronal processes. Strong expression in the hippocampus, neuron-rich dendate granule cells, and pyramidal cell layers. Highly expressed in neurons of the cerebral cortex. Also expressed in the cerebellar cortex, deep cerebellar nuclei, thalamus, and basal ganglia. No expression in muscle cells.
    • Sequence similarities

      Belongs to the syntrophin family.
      Contains 1 PDZ (DHR) domain.
      Contains 1 PH domain.
    • Domain

      The PDZ domain binds to the last three or four amino acids of DGKZ. The association with dystrophin or related proteins probably leaves the PDZ domain available to recruit proteins to the membrane.
    • Cellular localization

      Cytoplasm > cytoskeleton. Nucleus. Mainly cytoplasmic and weakly nuclear.
    • Information by UniProt
    • Database links

    • Alternative names

      • G1SYN antibody
      • Gamma 1 syntrophin antibody
      • Gamma-1-syntrophin antibody
      • gamma1 syntrophin antibody
      • OTTHUMP00000226271 antibody
      • OTTHUMP00000226272 antibody
      • OTTHUMP00000226273 antibody
      • OTTHUMP00000226275 antibody
      • SNTG 1 antibody
      • Sntg1 antibody
      • SNTG1_HUMAN antibody
      • SYN 4 antibody
      • SYN4 antibody
      • Synotrophin gamma 1 antibody
      • Syntrophin 4 antibody
      • Syntrophin gamma 1 antibody
      • Syntrophin-4 antibody
      see all

    Images

    • All lanes : Anti-SYN4 antibody [EPR8707] (ab133767) at 1/1000 dilution

      Lane 1 : Mouse brain lysate
      Lane 2 : Rat brain lysate
      Lane 3 : Human fetal brain lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labelled Goat anti Rabbit IgG at 1/2000 dilution

      Predicted band size: 58 kDa

    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References

    ab133767 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab133767.
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