Key features and details
- Rabbit polyclonal to Synapsin I (phospho S9)
- Suitable for: WB, ICC/IF
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-Synapsin I (phospho S9) antibody
See all Synapsin I primary antibodies
DescriptionRabbit polyclonal to Synapsin I (phospho S9)
Tested applicationsSuitable for: WB, ICC/IFmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide corresponding to Human Synapsin I (phospho S9). Phospho specific peptide corresponding to residues surrounding Serine 9 of Human Synapsin I.
Database link: P17600
- Mouse brain tissue extract; HeLa cells.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 49% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab194778 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/2000. Predicted molecular weight: 74 kDa.|
|ICC/IF||1/100 - 1/200.|
FunctionNeuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level.
Involvement in diseaseDefects in SYN1 are a cause of epilepsy X-linked with variable learning disabilities and behavior disorders [MIM:300491]. XELBD is characterized by variable combinations of epilepsy, learning difficulties, macrocephaly, and aggressive behavior.
Sequence similaritiesBelongs to the synapsin family.
modificationsSubstrate of at least four different protein kinases. It is probable that phosphorylation plays a role in the regulation of synapsin-1 in the nerve terminal. Phosphorylated upon DNA damage, probably by ATM or ATR.
Cellular localizationCell junction > synapse. Golgi apparatus.
- Information by UniProt
- Brain protein 4.1 antibody
- SYN 1 antibody
- SYN 1a antibody
ab194778 has been referenced in 1 publication.
- Alvarez-Carbonell D et al. Cross-talk between microglia and neurons regulates HIV latency. PLoS Pathog 15:e1008249 (2019). PubMed: 31887215