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    synaptobrevin-antibody-ab28362.pdf

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Neuroscience Neurotransmission Secretory Vesicles SNAPs & SNAREs
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Anti-Synaptobrevin antibody (ab28362)

  • Datasheet
  • SDS
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Key features and details

  • Sheep polyclonal to Synaptobrevin
  • Reacts with: Rat
  • Isotype: IgG

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Rabbit Anti-Sheep IgG H&L (HRP) (ab6747)

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Overview

  • Product name

    Anti-Synaptobrevin antibody
    See all Synaptobrevin primary antibodies
  • Description

    Sheep polyclonal to Synaptobrevin
  • Host species

    Sheep
  • Species reactivity

    Reacts with: Rat
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • Positive control

    • Rat synaptic vesicles
  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing the problem with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.

    One factor contributing to the crisis is the use of antibodies that are not suitable. This can lead to misleading results and the use of incorrect data informing project assumptions and direction. To help address this challenge, we have introduced an application and species grid on our primary antibody datasheets to make it easy to simplify identification of the right antibody for your needs.

    Learn more here.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    Preservative: 0.08% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • Purity

    Ammonium Sulphate Precipitation
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Neuroscience
    • Neurotransmission
    • Secretory Vesicles
    • SNAPs & SNAREs
    • Neuroscience
    • Cell Type Marker
    • Neuron marker
    • Synapse marker
    • Cancer
    • Cancer Metabolism
    • Metabolic signaling pathway
    • Integration of energy metabolism
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Energy transfer pathways
    • Integration of energy
    • Metabolism
    • Types of disease
    • Cancer

Associated products

  • Isotype control

    • Sheep IgG - Isotype Control (ab37385)

Target

  • Relevance

    Synaptobrevins are highly conserved between vertebrates and invertebrates. It is a major constituent of synaptic vesicles and peptidergic secretory granules in all neurons examined so far. In addition, it is present on secretory granules of neuroendocrine cells. Synaptobrevins, Syntaxins, and the 25 kDa synaptosomal associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane.
  • Cellular localization

    Cytoplasmic vesicle › secretory vesicle › synaptic vesicle membrane. Single-pass type IV membrane protein. Cell junction > synapse > synaptosome. Isoform 3 is found in mitochondria, mitochondrial outer membrane.
  • Database links

    • Entrez Gene: 25624 Rat
    • SwissProt: Q63666 Rat
    • Unigene: 31977 Rat
    • Alternative names

      • SYB antibody
      • SYB1 antibody
      • Synaptobrevin 1 antibody
      • VAMP antibody
      • VAMP1 antibody
      • Vesicle associated membrane protein 1 antibody
      see all

    Protocols

    • Western blot protocols
    • Immunoprecipitation protocols

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download

    References (0)

    Publishing research using ab28362? Please let us know so that we can cite the reference in this datasheet.

    ab28362 has not yet been referenced specifically in any publications.

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