Anti-Synaptobrevin antibody (ab28362)

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Key features and details

  • Sheep polyclonal to Synaptobrevin
  • Reacts with: Rat
  • Isotype: IgG

Overview

  • Product name

    Anti-Synaptobrevin antibody
    See all Synaptobrevin primary antibodies

  • Description

    Sheep polyclonal to Synaptobrevin

  • Host species

    Sheep

  • Species reactivity

    Reacts with: Rat

  • Immunogen

    The details of the immunogen for this antibody are not available.

  • Positive control

    • Rat synaptic vesicles

  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing the problem with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.

    One factor contributing to the crisis is the use of antibodies that are not suitable. This can lead to misleading results and the use of incorrect data informing project assumptions and direction. To help address this challenge, we have introduced an application and species grid on our primary antibody datasheets to make it easy to simplify identification of the right antibody for your needs.

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Properties

Associated products

Target

  • Relevance

    Synaptobrevins are highly conserved between vertebrates and invertebrates. It is a major constituent of synaptic vesicles and peptidergic secretory granules in all neurons examined so far. In addition, it is present on secretory granules of neuroendocrine cells. Synaptobrevins, Syntaxins, and the 25 kDa synaptosomal associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane.

  • Cellular localization

    Cytoplasmic vesicle › secretory vesicle › synaptic vesicle membrane. Single-pass type IV membrane protein. Cell junction > synapse > synaptosome. Isoform 3 is found in mitochondria, mitochondrial outer membrane.

  • Database links

    • Alternative names

      • SYB antibody
      • SYB1 antibody
      • Synaptobrevin 1 antibody
      • VAMP antibody
      • VAMP1 antibody
      • Vesicle associated membrane protein 1 antibody
      see all

    References (0)

    Publishing research using ab28362? Please let us know so that we can cite the reference in this datasheet.

    ab28362 has not yet been referenced specifically in any publications.

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