Key features and details
- Rabbit polyclonal to Synaptopodin 2
- Suitable for: ICC/IF
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Synaptopodin 2 antibody
See all Synaptopodin 2 primary antibodies
DescriptionRabbit polyclonal to Synaptopodin 2
Tested applicationsSuitable for: ICC/IFmore details
Species reactivityReacts with: Human
- SH-SY5Y cells.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), 59% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab220345 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use a concentration of 0.25 - 2 µg/ml.|
FunctionHas an actin-binding and actin-bundling activity.
Tissue specificitySkeletal muscle-specific.
Sequence similaritiesBelongs to the synaptopodin family.
Contains 1 PDZ (DHR) domain.
Cellular localizationNucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm in a differentiation-dependent and stress-induced fashion. Localizes to the Z-disk in mature striated muscle. The nuclear export is XPO1-dependent (By similarity). Localized in a fiber-like pattern. partly overlapping with filamentous actin.
- Information by UniProt
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ab220345 has been referenced in 2 publications.
- Cai X et al. Silence of IGFBP7 suppresses apoptosis and epithelial mesenchymal transformation of high glucose induced-podocytes. Exp Ther Med 16:1095-1102 (2018). PubMed: 30112052
- Li Y et al. Overexpression of KLF5 inhibits puromycin-induced apoptosis of podocytes. Mol Med Rep 18:3843-3849 (2018). PubMed: 30106142