Anti-Synaptotagmin antibody (ab51172)
Key features and details
- Rabbit polyclonal to Synaptotagmin
- Suitable for: ELISA, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Synaptotagmin antibody
See all Synaptotagmin primary antibodies -
Description
Rabbit polyclonal to Synaptotagmin -
Host species
Rabbit -
Tested applications
Suitable for: ELISA, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
A synthesized non-phosphopeptide derived from human Synaptotagmin around the phosphorylation site of threonine 202.
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Positive control
- Human breast carcinoma tissue
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab51172 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA |
1/10000.
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IHC-P |
Use at an assay dependent concentration.
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Notes |
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ELISA
1/10000. |
IHC-P
Use at an assay dependent concentration. |
Target
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Function
May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. -
Sequence similarities
Belongs to the synaptotagmin family.
Contains 2 C2 domains. -
Domain
The first C2 domain mediates Ca(2+)-dependent phospholipid binding.
The second C2 domain mediates interaction with Stonin 2. -
Cellular localization
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane. Synaptic vesicles and chromaffin granules. - Information by UniProt
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Database links
- Entrez Gene: 127833 Human
- Entrez Gene: 6857 Human
- Entrez Gene: 6860 Human
- Entrez Gene: 6861 Human
- Entrez Gene: 84258 Human
- Entrez Gene: 20979 Mouse
- Entrez Gene: 20980 Mouse
- Entrez Gene: 24805 Rat
see all -
Alternative names
- HsT1192 antibody
- MYSPC antibody
- P65 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab51172 has been referenced in 1 publication.
- Legate KR et al. Comparative phenotypic analysis of the two major splice isoforms of phosphatidylinositol phosphate kinase type I? in vivo. J Cell Sci 125:5636-46 (2012). PubMed: 22976293