Key features and details
- Rabbit polyclonal to Synaptotagmin
- Suitable for: ELISA, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Synaptotagmin antibody
See all Synaptotagmin primary antibodies
DescriptionRabbit polyclonal to Synaptotagmin
SpecificityThis antibody reacts with endogenous levels of total Synaptotagmin protein.
Tested applicationsSuitable for: ELISA, IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
A synthesized non-phosphopeptide derived from human Synaptotagmin around the phosphorylation site of threonine 202.
- Human breast carcinoma tissue
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 0.87% Sodium chloride, PBS
Concentration information loading...
PurityImmunogen affinity purified
Purification notesThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Pathways and Processes
- Metabolic signaling pathways
- Energy transfer pathways
- Integration of energy
Our Abpromise guarantee covers the use of ab51172 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use at an assay dependent concentration.|
FunctionMay have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
Sequence similaritiesBelongs to the synaptotagmin family.
Contains 2 C2 domains.
DomainThe first C2 domain mediates Ca(2+)-dependent phospholipid binding.
The second C2 domain mediates interaction with Stonin 2.
Cellular localizationCytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane. Synaptic vesicles and chromaffin granules.
- Information by UniProt
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ab51172 has been referenced in 1 publication.
- Legate KR et al. Comparative phenotypic analysis of the two major splice isoforms of phosphatidylinositol phosphate kinase type I? in vivo. J Cell Sci 125:5636-46 (2012). PubMed: 22976293