Overview

  • Product name

    Anti-Synaptotagmin VII antibody
    See all Synaptotagmin VII primary antibodies
  • Description

    Rabbit polyclonal to Synaptotagmin VII
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    antigen, corresponding to amino acids 51-181 of Human Synaptotagmin VII.

  • Positive control

    • Synaptotagmin VII-transfected HEK293T lysate; Human kidney tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab121383 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500.

Target

  • Function

    May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.
  • Tissue specificity

    Expressed in a variety of adult and fetal tissues.
  • Sequence similarities

    Belongs to the synaptotagmin family.
    Contains 2 C2 domains.
  • Domain

    The second C2 domain/C2B is responsible for SYNCRIP binding.
  • Cellular localization

    Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • IPCA 7 antibody
    • IPCA-7 antibody
    • IPCA7 antibody
    • PCANAP7 antibody
    • prostate cancer associated protein 7 antibody
    • Prostate cancer-associated protein 7 antibody
    • Synaptotagmin VII antibody
    • Synaptotagmin-7 antibody
    • Synaptotagmin7 antibody
    • SynaptotagminVII antibody
    • Synatotagmin 7 antibody
    • SYT 7 antibody
    • SYT VII antibody
    • SYT7 antibody
    • SYT7_HUMAN antibody
    • SytVII antibody
    see all

Images

  • All lanes : Anti-Synaptotagmin VII antibody (ab121383) at 1/250 dilution

    Lane 1 : vector only transfected HEK293T lysate
    Lane 2 : Synaptotagmin VII-transfected HEK293T lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa))

    Developed using the ECL technique.


    10-20% SDS PAGE
  • ab121383 at 1/25 dilution staining Synaptotagmin VII in Paraffin-embedded Human kidney tissue by Immunohistochemistry, showing strong cytoplasmic positivity, with a granular pattern, in cells in tubules.

References

ab121383 has not yet been referenced specifically in any publications.

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