Anti-Syndecan-1 antibody [B-A38], prediluted (ab1410)

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Key features and details

  • Mouse monoclonal [B-A38] to Syndecan-1, prediluted
  • Reacts with: Human
  • Isotype: IgG1

Overview

  • Product name

    Anti-Syndecan-1 antibody [B-A38], prediluted
    See all Syndecan-1 primary antibodies

  • Description

    Mouse monoclonal [B-A38] to Syndecan-1, prediluted

  • Host species

    Mouse

  • Species reactivity

    Reacts with: Human

  • Immunogen

    U266 cell line derived from Hodgkins disease

  • Positive control

    • Tonsil

  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing the problem with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.

    One factor contributing to the crisis is the use of antibodies that are not suitable. This can lead to misleading results and the use of incorrect data informing project assumptions and direction. To help address this challenge, we have introduced an application and species grid on our primary antibody datasheets to make it easy to simplify identification of the right antibody for your needs.

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Applications

  • Application notes
    IHC:
    This antibody is pre-diluted for use with an ABC system.
    For formalin fixed paraffin embedded sections, perform heat mediated antigen retrieval before commencing with IHC.

    • Target

    • Function

      Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.

    • Sequence similarities

      Belongs to the syndecan proteoglycan family.

    • Cellular localization

      Membrane.
    • Information by UniProt

    • Database links

      • Alternative names

        • CD_antigen antibody
        • CD138 antibody
        • CD138 antigen antibody
        • heparan sulfate proteoglycan fibroblast growth factor receptor antibody
        • SDC antibody
        • Sdc1 antibody
        • SDC1_HUMAN antibody
        • SYND1 antibody
        • Syndecan 1 antibody
        • Syndecan antibody
        • syndecan proteoglycan 1 antibody
        • Syndecan-1 antibody
        see all

      References (2)

      Publishing research using ab1410? Please let us know so that we can cite the reference in this datasheet.

      ab1410 has been referenced in 2 publications.

      • Sun RX  et al. Large scale and clinical grade purification of syndecan-1+ malignant plasma cells. J Immunol Methods 205:73-9 (1997). PubMed: 9236917
      • Carbone A  et al. Reed-Sternberg cells of classical Hodgkin's disease react with the plasma cell-specific monoclonal antibody B-B4 and express human syndecan-1. Blood 89:3787-94 (1997). PubMed: 9160685

      Customer reviews and Q&As

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      Question

      Are there any images available for this antibody?

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      Answer

      I have attached an image of tonsil section stained with ab1410.

      I hope this is helpful. Please contact us again if you have any further questions.

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      Question

      Hello,

      I am writing to ask about your productab1410. For CD138, I have heard of clone b-b4, but not BC/B-B4. Is this a mixture of 2 antibodies? Or is there a typo and it's actually B-B4?Also, your site says it's 6ml, but what is the concentration?

      Thanks,

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      Answer

      Thank you for your inquiry.

      I can confirm that clone BC/B-B4 is a sub-clone of B-B4 and therefore binds the same epitope and has the same characteristics.

      Unfortunately, the concentration of ab1410 is proprietary. This product is designed as ready-to-use solution and should be added to the slides neat.

      I hope this information was helpful. Please do not hesitate to contact me again with any further questions.

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