Key features and details
- Rabbit polyclonal to Syntaxin 16 - Drosophila Golgi/Trans-Golgi Marker
- Suitable for: WB
- Reacts with: Drosophila melanogaster
- Isotype: IgG
Product nameAnti-Syntaxin 16 antibody - Drosophila Golgi/Trans-Golgi Marker
See all Syntaxin 16 primary antibodies
DescriptionRabbit polyclonal to Syntaxin 16 - Drosophila Golgi/Trans-Golgi Marker
Tested applicationsSuitable for: WBmore details
Unsuitable for: ICC/IF
Species reactivityReacts with: Drosophila melanogaster
Synthetic peptide corresponding to Drosophila melanogaster Syntaxin 16 aa 200-300 conjugated to keyhole limpet haemocyanin.
(Peptide available as
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab32340 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 2.5 µg/ml. Detects a band of approximately 40 kDa (predicted molecular weight: 40 kDa).|
FunctionSNARE involved in vesicular transport from the late endosomes to the trans-Golgi network.
Involvement in diseaseGenetic variations in STX16 may be a cause of pseudohypoparathyroidism type 1B (PHP1B) [MIM:603233]. Pseudohypoparathyroidism refers to a heterogeneous group of disorders characterized by resistance to parathyroid hormone (PTH). PHP1B is characterized by PTH-resistant hypocalcemia and hyperphosphatemia. Patients affected with PHP1B lack developmental defects characteristic of Albright hereditary osteodystrophy, and typically show no other endocrine abnormalities besides resistance to PTH. In some cases microdeletions involving STX16 appear to cause loss of methylation at exon A/B of the GNAS gene, resulting in PHP1B.
Sequence similaritiesBelongs to the syntaxin family.
Contains 1 t-SNARE coiled-coil homology domain.
Cellular localizationCytoplasm and Golgi apparatus membrane.
- Information by UniProt
- hsyn16 antibody
- MGC90328 antibody
- Stx16 antibody
Anti-Syntaxin 16 antibody - Drosophila Golgi/Trans-Golgi Marker (ab32340) at 1 µg/ml +
Schneider L2 whole cell lysate (ab14893) at 20 µg
IRDye 680 Conjugated Goat Anti-Rabbit IgG (H+L) at 1/15000 dilution
Performed under reducing conditions.
Predicted band size: 40 kDa
Observed band size: 40 kDa
ab32340 has been referenced in 4 publications.
- Bellec K et al. Stratum recruits Rab8 at Golgi exit sites to regulate the basolateral sorting of Notch and Sanpodo. Development 145:N/A (2018). PubMed: 29967125
- Charng WL et al. Drosophila Tempura, a novel protein prenyltransferase a subunit, regulates notch signaling via Rab1 and Rab11. PLoS Biol 12:e1001777 (2014). ICC/IF ; Drosophila melanogaster . PubMed: 24492843
- Hornbruch-Freitag C et al. Drosophila Swiprosin-1/EFHD2 accumulates at the prefusion complex stage during Drosophila myoblast fusion. J Cell Sci 124:3266-78 (2011). ICC/IF ; Drosophila melanogaster . PubMed: 21896648
- Tiklová K et al. Epithelial septate junction assembly relies on melanotransferrin iron binding and endocytosis in Drosophila. Nat Cell Biol 12:1071-7 (2010). WB, IHC-P ; Drosophila melanogaster . PubMed: 20935638