Overview

Description

  • Nature
    Synthetic
  • Source
    Synthetic
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      GIGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKCCKKP
    • Molecular weight
      4 kDa
    • Amino acids
      24 to 64
    • Additional sequence information
      Modifications: Disulphide bridge. Sequence refers to the mature full length protein.

Specifications

Our Abpromise guarantee covers the use of ab174985 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    HPLC

  • Form
    Lyophilised
  • Additional notes

    Previously labelled as beta 2 Defensin.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

  • Reconstitution
    It is recommended vials be centrifuged prior to opening. Water can be used to prepare stock solutions of 20 µmol.L-1. Stock solutions with up to 30% DMSO/water can also be prepared.

General Info

  • Alternative names
    • BD 2
    • BD-2
    • BD2
    • beta 2
    • beta 2 Defensin
    • Beta defensin 2
    • Beta defensin 4B
    • Beta-defensin 2
    • Beta-defensin 4A
    • DEF B2
    • DEF B4
    • DEFB 102
    • DEFB 2
    • DEFB 4
    • DEFB102
    • DEFB2
    • DEFB2, formerly
    • DEFB4
    • DEFB4, formerly
    • DEFB4B
    • DEFB4P
    • Defensin
    • Defensin beta 2
    • Defensin, beta 4
    • Defensin, beta 4, pseudogene
    • Defensin, beta 4A
    • Defensin, beta 4B
    • Defensin, beta, 2, formerly
    • Defensin, beta, 4, formerly
    • DFB4A_HUMAN
    • HBD 2
    • hBD-2
    • HBD2
    • mBD-2
    • SAP 1
    • SAP1
    • Skin antimicrobial peptide 1
    • Skin-antimicrobial peptide 1
    see all
  • Function
    Has antibacterial activity.
  • Tissue specificity
    Expressed in the skin and respiratory tract.
  • Sequence similarities
    Belongs to the beta-defensin family. LAP/TAP subfamily.
  • Cellular localization
    Secreted.
  • Information by UniProt

References

ab174985 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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