Synthetic Human Macrophage Inflammatory Protein 1 alpha / CCL3 (Biotin) (ab176081)
Key features and details
- Expression system: Synthetic
- Suitable for: HPLC
Description
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Product name
Synthetic Human Macrophage Inflammatory Protein 1 alpha / CCL3 (Biotin)
See all Macrophage Inflammatory Protein 1 alpha / CCL3 proteins and peptides -
Expression system
Synthetic -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Synthetic -
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Species
Human -
Sequence
ASLAADTP TACCFSYTSR QIPQNFIADY FETSSQCSKP GVIFLTKRSR QVCADPSEEW VQKYVSDLEL SA-Linker-K(Biotin) -
Predicted molecular weight
8 kDa -
Amino acids
23 to 92 -
Additional sequence information
Mature protein. Linker used is 8-amino-3,6-dioxaoctanoic acid.
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Conjugation
Biotin
Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab176081 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
HPLC
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Form
Lyophilized -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Lyophilized from water/acetonitrile/TFA to generate the TFA salt form.
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ReconstitutionIt is recommended vials be centrifuged prior to opening. Water can be used to prepare stock solutions of 20 µmol.L-1. Stock solutions with up to 30% DMSO/water can also be prepared.
General Info
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Alternative names
- C C motif chemokine 3
- CCL 3
- CCL3
see all -
Function
Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). -
Sequence similarities
Belongs to the intercrine beta (chemokine CC) family. -
Post-translational
modificationsN-terminal processed form LD78-alpha(4-69) is produced by proteolytic cleavage after secretion from HTLV1-transformed T-cells. -
Cellular localization
Secreted. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab176081 has not yet been referenced specifically in any publications.