Synthetic Human MCP2 protein (Animal Free) (ab175171)
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Overview
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Product nameSynthetic Human MCP2 protein (Animal Free)
See all MCP2 proteins and peptides -
Protein lengthProtein fragment
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DescriptionSynthetic Human MCP2 protein
Description
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NatureSynthetic
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SourceSynthetic
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Amino Acid Sequence
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Accession
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SpeciesHuman
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SequenceQPDSVSIPITCCFNVINRKIPIQRLESYTRITNIQCPKEAVIFKTKRGKE VCADPKERWVRDSMKHLDQI FQNLK
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Molecular weight9 kDa
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Amino acids24 to 98
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab175171 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
HPLC
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FormLyophilised
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Information available upon request.
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ReconstitutionIt is recommended vials be centrifuged prior to opening. Water can be used to prepare stock solutions of 20 µmol.L-1. Stock solutions with up to 30% DMSO/water can also be prepared.
General Info
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Alternative names
- Ccl8
- CCL8_HUMAN
- HC14
see all -
FunctionChemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8.
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Tissue specificityHighest expression found in the small intestine and peripheral blood cells. Intermediate levels seen in the heart, placenta, lung, skeletal muscle, thymus, colon, ovary, spinal cord and pancreas. Low levels seen in the brain, liver, spleen and prostate.
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Sequence similaritiesBelongs to the intercrine beta (chemokine CC) family.
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Post-translational
modificationsN-terminal processed form MCP-2(6-76) is produced by proteolytic cleavage after secretion from peripheral blood monocytes. -
Cellular localizationSecreted.
- Information by UniProt
Datasheets and documents
References
ab175171 has not yet been referenced specifically in any publications.
