Synthetic Human MIP-3 beta/CCL19 protein (Biotin) (ab176065)
Key features and details
- Expression system: Synthetic
- Suitable for: HPLC
Description
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Product name
Synthetic Human MIP-3 beta/CCL19 protein (Biotin)
See all MIP-3 beta/CCL19 proteins and peptides -
Expression system
Synthetic -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Synthetic -
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Species
Human -
Sequence
GTNDAEDCCL SVTQKPIPGY IVRNFHYLLIKDGCRVPAVVFTTLRGRQLC APPDQPWVERIIQRLQRTSA KMKRRSSK(Biotin)-NH2 -
Predicted molecular weight
9 kDa -
Amino acids
22 to 98 -
Additional sequence information
Mature protein.
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Conjugation
Biotin
Specifications
Our Abpromise guarantee covers the use of ab176065 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
HPLC
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Form
Lyophilized -
Additional notes
Biotin incorporated at indicated position in a molar ratio of biotin:peptide of 1:1.
This product was previously labelled as Macrophage Inflammatory Protein 3 beta
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Lyophilized from water/acetonitrile/TFA to generate the TFA salt form.
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ReconstitutionIt is recommended vials be centrifuged prior to opening. Water can be used to prepare stock solutions of 20 µmol.L-1. Stock solutions with up to 30% DMSO/water can also be prepared.
General Info
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Alternative names
- Beta chemokine exodus 3
- Beta-chemokine exodus-3
- C C chemokine ligand 19
see all -
Function
May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Specifically binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. -
Tissue specificity
Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach. -
Sequence similarities
Belongs to the intercrine beta (chemokine CC) family. -
Cellular localization
Secreted. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab176065 has not yet been referenced specifically in any publications.