Product nameAnti-SYT1 antibody
See all SYT1 primary antibodies
DescriptionChicken polyclonal to SYT1
Specificityab53484 recognizes SYT1.
Tested applicationsSuitable for: ICC/IF, WBmore details
Species reactivityReacts with: Mouse, Human, Apteronotus leptorhynchus
Synthetic peptide corresponding to SYT1 conjugated to keyhole limpet haemocyanin. Shared between the human (NP_005630, NCBI) and mouse (NP_033332, NCBI) sequences.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferPreservative: 0.02% Sodium Azide
Constituents: PBS, pH 7.2
Concentration information loading...
Our Abpromise guarantee covers the use of ab53484 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/1000. Predicted molecular weight: 48 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionMay have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.
Sequence similaritiesBelongs to the synaptotagmin family.
Contains 2 C2 domains.
DomainThe first C2 domain mediates Ca(2+)-dependent phospholipid binding.
The second C2 domain mediates interaction with SV2A and STN2.
Cellular localizationCytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Cytoplasmic vesicle > secretory vesicle > chromaffin granule membrane. Cytoplasm. Synaptic vesicles and chromaffin granules.
- Information by UniProt
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Anti-SYT1 antibody (ab53484) at 1/1000 dilution
Predicted band size: 48 kDa
Observed band size: 60 kDa why is the actual band size different from the predicted?
ab53484 has not yet been referenced specifically in any publications.