Overview

  • Product name

  • Description

    Goat polyclonal to SYT2
  • Host species

    Goat
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse
    Predicted to work with: Rat, Human
  • Immunogen

    Synthetic peptide:

    C-KPEEEVDALLGKNK

    , corresponding to C terminal amino acids 406-419 of Human SYT2 (NP_796376.2).

  • Positive control

    • Mouse lung lysate

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab109987 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 47 kDa).

Target

  • Function

    May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
  • Sequence similarities

    Belongs to the synaptotagmin family.
    Contains 2 C2 domains.
  • Domain

    The first C2 domain mediates Ca(2+)-dependent phospholipid binding.
    The second C2 domain mediates interaction with Stonin 2.
  • Cellular localization

    Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Cytoplasmic vesicle > secretory vesicle > chromaffin granule membrane. Synaptic vesicles and chromaffin granules.
  • Information by UniProt
  • Database links

  • Alternative names

    • Synaptotagmin 2 antibody
    • Synaptotagmin II antibody
    • Synaptotagmin-2 antibody
    • Synaptotagmin2 antibody
    • SynaptotagminII antibody
    • SYT 2 antibody
    • Syt II antibody
    • Syt2 antibody
    • SYT2_HUMAN antibody
    • SytII antibody
    see all

Images

  • Anti-SYT2 antibody (ab109987) at 0.1 µg/ml + Mouse lung lysate (in RIPA buffer) at 35 µg

    Developed using the ECL technique.

    Predicted band size: 47 kDa
    Observed band size: 50 kDa
    why is the actual band size different from the predicted?


    Exposure time: 1 hour

References

ab109987 has not yet been referenced specifically in any publications.

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