Overview

  • Product name

  • Description

    Rabbit polyclonal to TAB1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
    Predicted to work with: Chicken, Cow, Pig, Rhesus monkey
  • Immunogen

    Recombinant fragment within Human TAB1 (internal sequence). The exact sequence is proprietary.
    Database link: Q15750

  • Positive control

    • WB: PC-12, Rat2, Neuro-2a, C8D30, NIH/3T3 and RAW 264.7 whole cell extracts; A431 and MOLT-4 whole cell lysates. ICC/IF: HeLa cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab227210 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/100 - 1/1000.
WB 1/500 - 1/3000. Predicted molecular weight: 55 kDa.

Target

  • Function

    May be an important signaling intermediate between TGFB receptors and MAP3K7/TAK1. May play an important role in mammalian embryogenesis.
  • Tissue specificity

    Ubiquitous.
  • Sequence similarities

    Contains 1 PP2C-like domain.
  • Post-translational
    modifications

    Monoubiquitinated. Deubiquitinated by Y.enterocolitica YopP.
  • Information by UniProt
  • Database links

  • Alternative names

    • 2310012M03Rik antibody
    • 3'-Tab1 antibody
    • MAP3K7IP 1 antibody
    • MAP3K7IP1 antibody
    • MGC57664 antibody
    • Mitogen activated protein kinase kinase kinase 7 interacting protein 1 antibody
    • Mitogen-activated protein kinase kinase kinase 7-interacting protein 1 antibody
    • TAB 1 antibody
    • TAB1 antibody
    • TAB1_HUMAN antibody
    • TAK1 binding protein 1 antibody
    • TAK1-binding protein 1 antibody
    • TGF beta activated kinase 1 binding protein 1 antibody
    • TGF-beta activated kinase 1/MAP3K7 binding protein 1 antibody
    • TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 antibody
    • TGF-beta-activated kinase 1-binding protein 1 antibody
    • Transforming growth factor beta activated kinase binding protein 1 antibody
    see all

Images

  • All lanes : Anti-TAB1 antibody (ab227210) at 1/1000 dilution

    Lane 1 : A431 (human epidermoid carcinoma cell line) whole cell lysate
    Lane 2 : MOLT-4 (human lymphoblastic leukemia cell line) whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 55 kDa



    7.5% SDS-PAGE gel.

  • All lanes : Anti-TAB1 antibody (ab227210) at 1/500 dilution

    Lane 1 : Neuro-2a (mouse neuroblastoma cell line) whole cell extract
    Lane 2 : C8D30 whole cell extract
    Lane 3 : NIH/3T3 (mouse embryo fibroblast cell line) whole cell extract
    Lane 4 : RAW 264.7 (mouse macrophage cell line transformed with Abelson murine leukemia virus) whole cell extract

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 55 kDa



    10% SDS-PAGE gel.

  • All lanes : Anti-TAB1 antibody (ab227210) at 1/500 dilution

    Lane 1 : PC-12 (rat adrenal gland pheochromocytoma cell line) whole cell lysate
    Lane 2 : Rat2 (rat fibroblast cell line) whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 55 kDa



    10% SDS-PAGE gel.

  • Paraformaldehyde-fixed HeLa (human epithelial cell line from cervix adenocarcinoma) cells stained for TAB1 (green) using ab227210 at 1/200 dilution in ICC/IF.

    Lower panel: Merged with DNA probe.

References

ab227210 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab227210.
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