Key features and details
- Rabbit polyclonal to TAB3
- Suitable for: IP
- Reacts with: Human
- Isotype: IgG
Product nameAnti-TAB3 antibody
See all TAB3 primary antibodies
DescriptionRabbit polyclonal to TAB3
Tested applicationsSuitable for: IPmore details
Species reactivityReacts with: Human
Synthetic peptide within Human TAB3 aa 650-700. The exact sequence is proprietary.
Database link: Q8N5C8
- IP: HEK-293T whole cell lysate.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7
Preservative: 0.09% Sodium azide
Constituent: Tris citrate/phosphate
pH 7 to 8
Concentration information loading...
PurityImmunogen affinity purified
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab264287 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at 2-10 µg/mg of lysate.
Use at 2-10 µg/mg of lysate.
FunctionAdapter linking MAP3K7/TAK1 and TRAF6 or TRAF2. Mediator of MAP3K7 activation, respectively in the IL1 and TNF signaling pathways. Plays a role in activation of NF-kappa-B and AP1 transcription factor. Isoform 2 may be an oncogenic factor.
Tissue specificityWidely expressed. Constitutively overexpressed in certain tumor tissues. Isoform 1 is a major transcript while isoform 2 is a minor transcript.
Sequence similaritiesContains 1 CUE domain.
Contains 1 RanBP2-type zinc finger.
modificationsUbiquitinated; following IL1 stimulation or TRAF6 overexpression.
- Information by UniProt
- MAP3K7IP 3 antibody
- Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 antibody
- NAP1 antibody
TAB3 was immunoprecipitated from 1mg of HEK-293T (Human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate with ab264287 at 6 µg per reaction. Western blot was performed from the immunoprecipitate using ab264287 at 1 µg/ml.
Lane 1: ab264287 IP in HEK-293T whole cell lysate.
Lane 2: Control IgG.
Exposure time: 3 mins.
Cells prepared using NETN lysis buffer.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab264287 has not yet been referenced specifically in any publications.