Overview

  • Product name

  • Description

    Rabbit polyclonal to TAF1C
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Recombinant fragment corresponding to Human TAF1C aa 72-320 (internal sequence).
    Database link: Q15572

  • Positive control

    • WB: Extracts from 293T, MCF7 and mouse thymus. IHC-P: Mouse lung tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab210750 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200.
WB 1/500 - 1/2000. Predicted molecular weight: 95 kDa.

Target

  • Function

    Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3.
  • Post-translational
    modifications

    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • RNA polymerase I-specific TBP-associated factor 110 kDa antibody
    • SL1 antibody
    • Taf1c antibody
    • TAF1C_HUMAN antibody
    • TAFI110 antibody
    • TAFI95 antibody
    • TATA box binding protein associated factor 1C antibody
    • TATA box-binding protein-associated factor 1C antibody
    • TATA box-binding protein-associated factor RNA polymerase I subunit C antibody
    • TBP associated factor 1C antibody
    • TBP associated factor RNA polymerase I 95 kDa antibody
    • TBP associated factor, RNA polymerase I, 110-KD antibody
    • TBP-associated factor 1C antibody
    • Transcription initiation factor SL1/TIF-IB subunit C antibody
    see all

Images

  • All lanes : Anti-TAF1C antibody (ab210750) at 1/500 dilution

    Lane 1 : Extracts from 293T cell line
    Lane 2 : Extracts from MCF7 cell line
    Lane 3 : Extracts from mouse thymus

    Predicted band size: 95 kDa

  • Immunohistochemical analysis of paraffin-embedded mouse lung tissue sections labeling TAF1C with ab210750 at a 1/100 dilution.

References

ab210750 has not yet been referenced specifically in any publications.

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