Overview

  • Product name

    Anti-TAF1C antibody [EPR11298]
    See all TAF1C primary antibodies
  • Description

    Rabbit monoclonal [EPR11298] to TAF1C
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IPmore details
    Unsuitable for: Flow Cyt,ICC/IF or IHC-P
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human TAF1C aa 800 to the C-terminus (Cysteine residue). The exact sequence is proprietary.
    Database link: Q15572

  • Positive control

    • HeLa, Jurkat and 293T cell lysates.
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab178690 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 95 kDa.
IP 1/10 - 1/100.
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF or IHC-P.
  • Target

    • Function

      Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3.
    • Post-translational
      modifications

      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Cellular localization

      Nucleus.
    • Information by UniProt
    • Database links

    • Alternative names

      • RNA polymerase I-specific TBP-associated factor 110 kDa antibody
      • SL1 antibody
      • Taf1c antibody
      • TAF1C_HUMAN antibody
      • TAFI110 antibody
      • TAFI95 antibody
      • TATA box binding protein associated factor 1C antibody
      • TATA box-binding protein-associated factor 1C antibody
      • TATA box-binding protein-associated factor RNA polymerase I subunit C antibody
      • TBP associated factor 1C antibody
      • TBP associated factor RNA polymerase I 95 kDa antibody
      • TBP associated factor, RNA polymerase I, 110-KD antibody
      • TBP-associated factor 1C antibody
      • Transcription initiation factor SL1/TIF-IB subunit C antibody
      see all

    Images

    • All lanes : Anti-TAF1C antibody [EPR11298] (ab178690) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : Jurkat cell lysate
      Lane 3 : 293T cell lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 95 kDa

    • Western blot analysis on immunoprecipitation pellet from 293T cell lysate using ab178690.

    References

    ab178690 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab178690.
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