Key features and details
- Goat polyclonal to Tafazzin / TAZ
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Tafazzin / TAZ antibody
See all Tafazzin / TAZ primary antibodies
DescriptionGoat polyclonal to Tafazzin / TAZ
SpecificityThis antibody is expected to recognise isoforms 1 to 4. (NP_000107.1; NP_851828.1; NP_851829.1; NP_851830.1, respectively).
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Dog, Chimpanzee
- Recombinant Human Tafazzin / TAZ protein (ab114664) can be used as a positive control in WB. Human heart lysate.
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, Tris buffered saline
Concentration information loading...
PurityImmunogen affinity purified
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab40004 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use at a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 33 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionSome isoforms may be involved in cardiolipin (CL) metabolism.
Tissue specificityHigh levels in cardiac and skeletal muscle. Up to 10 isoforms can be present in different amounts in different tissues. Most isoforms are ubiquitous. Isoforms that lack the N-terminus are found in leukocytes and fibroblasts, but not in heart and skeletal muscle. Some forms appear restricted to cardiac and skeletal muscle or to leukocytes.
Involvement in diseaseBarth syndrome
Sequence similaritiesBelongs to the taffazin family.
DomainThe hydrophilic domain may serve as an exposed loop interacting with other proteins.
Cellular localizationCytoplasm and Membrane.
- Information by UniProt
- Barth syndrome antibody
- BTHS antibody
- Cardiomyopathy dilated 3A (X linked) antibody
Anti-Tafazzin / TAZ antibody (ab40004) at 0.3 µg/ml + Human Heart lysate in RIPA buffer at 35 µg
Predicted band size: 33 kDa
Observed band size: 28 kDa why is the actual band size different from the predicted?
Primary incubation was 1 hour. Detected by chemiluminescence.
ab40004 has been referenced in 1 publication.
- Gonzalvez F et al. Cardiolipin provides an essential activating platform for caspase-8 on mitochondria. J Cell Biol 183:681-96 (2008). WB ; Human . PubMed: 19001123