Anti-Tafazzin / TAZ antibody (ab176396)
Key features and details
- Rabbit polyclonal to Tafazzin / TAZ
- Suitable for: WB
- Reacts with: Rat, Human
- Isotype: IgG
Overview
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Product name
Anti-Tafazzin / TAZ antibody
See all Tafazzin / TAZ primary antibodies -
Description
Rabbit polyclonal to Tafazzin / TAZ -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Rat, Human
Predicted to work with: Chimpanzee, Rhesus monkey, Gorilla, Orangutan -
Immunogen
Synthetic peptide corresponding to Human Tafazzin/ TAZ aa 162-178 (internal sequence).
Sequence:MDFILEKLNHGDWVHIF
Database link: Q16635 -
Positive control
- Rat skeletal muscle, rat heart, rat liver, HeLa, SMMC and SCG cell lysates.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservatives: 0.025% Sodium azide, 0.025% Thimerosal (merthiolate)
Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab176396 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 0.1 - 0.5 µg/ml. Predicted molecular weight: 33 kDa.
The detection limit for Tafazzin / TAZ is approximately 10ng/lane under reducing conditions. |
Notes |
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WB
Use a concentration of 0.1 - 0.5 µg/ml. Predicted molecular weight: 33 kDa. The detection limit for Tafazzin / TAZ is approximately 10ng/lane under reducing conditions. |
Target
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Function
Some isoforms may be involved in cardiolipin (CL) metabolism. -
Tissue specificity
High levels in cardiac and skeletal muscle. Up to 10 isoforms can be present in different amounts in different tissues. Most isoforms are ubiquitous. Isoforms that lack the N-terminus are found in leukocytes and fibroblasts, but not in heart and skeletal muscle. Some forms appear restricted to cardiac and skeletal muscle or to leukocytes. -
Involvement in disease
Barth syndrome -
Sequence similarities
Belongs to the taffazin family. -
Domain
The hydrophilic domain may serve as an exposed loop interacting with other proteins. -
Cellular localization
Cytoplasm and Membrane. - Information by UniProt
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Database links
- Entrez Gene: 449590 Chimpanzee
- Entrez Gene: 101147380 Gorilla
- Entrez Gene: 6901 Human
- Entrez Gene: 363521 Rat
- Entrez Gene: 574297 Rhesus monkey
- Omim: 300394 Human
- SwissProt: Q6IV84 Chimpanzee
- SwissProt: Q6IV83 Gorilla
see all -
Alternative names
- Barth syndrome antibody
- BTHS antibody
- Cardiomyopathy dilated 3A (X linked) antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab176396 has not yet been referenced specifically in any publications.