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Epigenetics techniques and protocols

Use our Epigenetics protocols and troubleshooting tips to support you during your experiments. This page features popular Epigenetics applications such as chromatin immunoprecipitation (ChIP), RNA immunoprecipitation (RIP), and cross-linking immunoprecipitation (CLIP).

​Studying epigenetics with ChIP: a complete guide

 Find out about the different epigenetic factors that require ChIP analysis and determine which ChIP method is right for you. 

Find out about the different epigenetic factors, which require ChIP analysis, and determine which ChIP method is right for you. 
Discover the guide

ChIP assays resources

Find everything you need for your next ChIP experiment: from our in-depth guide to ChIP technique to kits, webinars, and protocols.

​ChIP-seq, ChIC/CUT&RUN-seq, CUT&Tag-seq

​Learn more about ChIP-seq and two new chromatin profiling methods, ChIC/CUT&RUN-seq and CUT&Tag-seq, with our guide, protocols, and webinars.

Chromatin structure resources

Understand chromatin structure and explore the methods to study chromatin structure and accessibility.

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Chromatin

Chromatin accessibility and architecture

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Article

Chromatin

Histone modifications

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Article

ChIC/CUT&RUN-seq protocol

ChIC/CUT&RUN-seq protocol

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Protocol

Going low in ChIP

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Article

DNA methylation and demethylation

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Article

Histone western blot protocol

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Protocol

RNA immunoprecipitation

DNA-RNA immunoprecipitation (DRIP) protocol

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Protocol

ChIP technique

Native chromatin immunoprecipitation protocol

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Protocol

ChIP technique

Chromatin preparation from tissues for ChIP

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Protocol

ChIP technique

Dual cross-linking ChIP protocol

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Article

ChIP technique

Cross-linking chromatin immunoprecipitation (X-ChIP) protocol

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Protocol

ChIP guide

638106952680000000

Article

RNA immunoprecipitation

RNA immunoprecipitation (RIP) protocol

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Protocol

Immunoprecipitation protocol

Immunoprecipitation protocol

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Protocol

Epigenetics application protocols guide

Epigenetics application guide

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Article

Nuclear extraction and fractionation protocol

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Protocol

Histone extraction protocol for western blot

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Protocol

Introduction to ChIP Principles with Troubleshooting Tips

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Video

ChIP troubleshooting tips

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Protocol

ChIP tips by Dr Andy Bannister of the Gurdon Institute

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Protocol

ChIP using plant samples - Arabidopsis

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Protocol

ChIP 2.0: Guide to advanced chromatin immunoprecipitation

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Article

Beyond ChIP Studies: the evolution of chromosome conformation capture

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Article

ChIP and ChIP-seq kits: from high sensitivity to fast protocols.

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Article

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