Key features and details
- Rabbit polyclonal to Talin 1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Talin 1 antibody
See all Talin 1 primary antibodies
DescriptionRabbit polyclonal to Talin 1
SpecificityThe immunogen sequence for ab137843 has 90% homology with Talin-2. We have not tested it for cross reactivity but we expect it will also react with Talin-2 based on this homology.
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Chicken, Cow, Zebrafish
A recombinant fragment corresponding to residues surrounding C terminal amino acids 2281-2537 of Human Talin 1 (UniProt ID: Q9Y490).
- 293T, A431, H1299, HepG2 and Raji cell lysates
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab137843 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 269 kDa.|
FunctionProbably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts.
Sequence similaritiesContains 1 FERM domain.
Contains 1 I/LWEQ domain.
Cellular localizationCell projection, ruffle membrane. Cytoplasm, cytoskeleton. Cell surface. Cell junction, focal adhesion. Colocalizes with LAYN at the membrane ruffles. Localized preferentially in focal adhesions than fibrillar adhesions (By similarity).
- Information by UniProt
- ILWEQ antibody
- Talin 1 antibody
- Talin antibody
ab137843 has not yet been referenced specifically in any publications.