Key features and details
- Estrogen receptor antagonist and partial agonist
- CAS Number: 54965-24-1
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 5 mM
- Form / State: Solid
- Source: Synthetic
Product nameTamoxifen citrate, Estrogen receptor antagonist and partial agonist
DescriptionEstrogen receptor antagonist and partial agonist
Competitive estrogen receptor antagonist and partial agonist. Inhibits estrogen dependent gene transcription and tumor growth. Additionally decreases cardiac infarction and inhibits Kir2.1, Kir2.2 and Kir2.3 potassium channels (IC50 values are 0.93, 0.87 and 0.31 µM, respectively).
Chemical name(Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine citrate
Storage instructionsStore at +4°C. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM and in ethanol to 5 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120656 has not yet been referenced specifically in any publications.