Key features and details
- Rabbit polyclonal to TANK/TRAF2
- Suitable for: IHC-P, WB
- Reacts with: Human, Pig
- Isotype: IgG
Product nameAnti-TANK/TRAF2 antibody
See all TANK/TRAF2 primary antibodies
DescriptionRabbit polyclonal to TANK/TRAF2
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Human, Pig
Recombinant fragment (His-T7-tag) corresponding to Human TANK/TRAF2 aa 131-369. (Expressed in E.coli).
LLHERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNIPDTATETQCSVP IQCTDKTDKQEALFKPQAKDDINRGAPSITSVTPRGLCRDEEDTSFESLS KFNVKFPPMDNDSTFLHSTPERPGILSPATSEAVCQEKFNMEFRDNPGNF VKTEETLFEIQGIDPIASAIQNLKTTDKTKPSNLVNTCIRTTLDRAACLP PGDHNALYVNSFPLLDPSDAPFPSLDSPGKAIRGPQQPI
Database link: Q92844
- IHC-P: Human kidney tissue. WB: Pig colon lysate; Recombinant human TANK/TRAF2 protein.
This product was previously labelled as TANK
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab233406 was purified by antigen-specific affinity chromatography followed by Protein A affinity chromatography.
Our Abpromise guarantee covers the use of ab233406 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 5 - 20 µg/ml.|
|WB||Use a concentration of 0.2 - 2 µg/ml. Predicted molecular weight: 48 kDa.|
FunctionActs as a regulator of TRAF function by maintaining them in a latent state. Overexpression inhibits TRAF2-mediated NF-kappa-B activation signaled by CD40, TNFR1 and TNFR2. Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation. May be involved in I-kappa-B-kinase (IKK) regulation; may function as an adapter for kinases such as TBK1 or IKBKE that can modulate IKK activity.
Sequence similaritiesContains 1 C2H2-type zinc finger.
modificationsPhosphorylated by IKBKE.
- Information by UniProt
- I TRAF antibody
- I-TRAF antibody
- ITRAF antibody
Formalin-fixed, paraffin-embedded human kidney tissue stained for TANK/TRAF2 using ab233406 at 20 µg/ml in immunohistochemical analysis. DAB staining.
Anti-TANK/TRAF2 antibody (ab233406) at 2 µg/ml + Recombinant human TANK/TRAF2 protein
Predicted band size: 48 kDa
Anti-TANK/TRAF2 antibody (ab233406) at 2 µg/ml + Pig colon lysate
Predicted band size: 48 kDa
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab233406 has not yet been referenced specifically in any publications.