Overview

  • Product name

  • Description

    Rabbit polyclonal to TARC/CCL17
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, Neutralising, Indirect ELISA, Sandwich ELISAmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant full length protein corresponding to Human TARC/CCL17.

  • General notes

     This product was previously labelled as TARC

     

Properties

  • Form

    Lyophilised:Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer

    Preservative: None
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab109836 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 11 kDa.

The detection limit for recombinant Human TARC/CCL17 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.

Neutralising Use a concentration of 2 - 3 µg/ml.

to yield one-half maximal inhibition [ND50] of the biological activity of Human TARC/CCL17 (100 ng/ml)

Indirect ELISA Use a concentration of 0.5 - 2 µg/ml.

ab109836 in conjunction with compatible secondary reagents, allows the detection of at least 0.2 - 0.4 ng/well of recombinant Human TARC/CCL17 (using 100 µl/well antibody solution).

Sandwich ELISA Use a concentration of 0.5 - 2 µg/ml. Can be paired for Sandwich ELISA with Rabbit polyclonal to TARC/CCL17 (Biotin) (ab84279).

ab109836 in conjunction with ab84279 as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant Human TARC/CCL17 (using 100 µl/well antibody solution).

Target

  • Function

    Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4.
  • Tissue specificity

    Expressed at high levels in thymus and at low levels in the lung, colon and small intestine.
  • Sequence similarities

    Belongs to the intercrine beta (chemokine CC) family.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • A-152E5.3 antibody
    • A152E53 antibody
    • ABCD 2 antibody
    • ABCD2 antibody
    • C-C motif chemokine 17 antibody
    • CC chemokine TARC antibody
    • CCL17 antibody
    • CCL17_HUMAN antibody
    • Chemokine CC Motif Ligand 17 antibody
    • MGC138271 antibody
    • MGC138273 antibody
    • SCYA17 antibody
    • Small Inducible Cytokine A17 antibody
    • Small Inducible Cytokine A17 Precursor antibody
    • Small Inducible Cytokine Subfamily A (Cys Cys) antibody
    • Small Inducible Cytokine Subfamily A (Cys Cys) Member 17 antibody
    • Small-inducible cytokine A17 antibody
    • T Cell Directed CC Chemokine antibody
    • Thymus and activation regulated chemokine antibody
    • Thymus and activation-regulated chemokine antibody
    see all

References

This product has been referenced in:

  • la Sala A  et al. Dendritic cells exposed to extracellular adenosine triphosphate acquire the migratory properties of mature cells and show a reduced capacity to attract type 1 T lymphocytes. Blood 99:1715-22 (2002). Read more (PubMed: 11861288) »
See 1 Publication for this product

Customer reviews and Q&As

Answer

Thanks for your inquiry. Based upon sequence homology, I would not expect any of the antibodies to cross react with mouse as there is only a 64% homology. Please let me know if you require further assistance.

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