Overview

  • Product name

    Anti-TAS2R43 antibody
  • Description

    Rabbit polyclonal to TAS2R43
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthesized peptide derived from an internal region of Human TAS2R43.

  • Positive control

    • COLO205 cell extract

Properties

Applications

Our Abpromise guarantee covers the use of ab138243 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 36 kDa.

Target

  • Function

    Gustducin-coupled receptor immplicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Activated by the sulfonyl amide sweeteners saccharin and acesulfame K. In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency. May acts as chemosensory receptors in airway epithelial cells to detect and eliminate potential noxious agents from the airways.
  • Tissue specificity

    Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Expressed in airway epithelia.
  • Sequence similarities

    Belongs to the G-protein coupled receptor T2R family.
  • Cellular localization

    Membrane. Cell projection > cilium membrane. In airway epithelial cells, localizes to motile cilia.
  • Information by UniProt
  • Database links

  • Alternative names

    • T2R43 antibody
    • T2R43_HUMAN antibody
    • T2R52 antibody
    • TAS2R43 antibody
    • Taste receptor type 2 member 43 antibody
    • Taste receptor type 2 member 52 antibody
    see all

Images

  • Anti-TAS2R43 antibody (ab138243) at 1/1000 dilution + COLO205 cell extract at 30 µg

    Developed using the ECL technique.

    Predicted band size: 36 kDa

References

ab138243 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab138243.
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